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一例脓疱型银屑病患者发生严重红皮病的病例。

A Case of Severe Erythroderma in a Patient with Pustular Psoriasis.

作者信息

Berko Joshua, Raps Christine, Cacic Quinlan, Stephen Robert, Fix Megan, Beaulieu Allison M

机构信息

University of Utah, Department of Emergency Medicine, Salt Lake City, Utah.

出版信息

Clin Pract Cases Emerg Med. 2024 Nov;8(4):388-390. doi: 10.5811/cpcem.24854.

DOI:10.5811/cpcem.24854
PMID:39704582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11661247/
Abstract

CASE PRESENTATION

A female patient with a known history of pustular psoriasis presented with sub-acute development of diffuse erythema and scaling of the skin with areas of exfoliation consistent with erythroderma. She was ill appearing and required admission and aggressive treatment with steroid-impregnated wet dressings, topical emollients, analgesics, and systemic immunosuppressants.

DISCUSSION

Erythroderma is a dermatologic emergency characterized by diffuse erythema and scaling spanning greater than 90% of skin surfaces and is associated with a mortality rate as high as 64%. It is initially a clinical diagnosis and needs to be recognized and aggressively treated expeditiously to improve chances of a good outcome.

摘要

病例介绍

一名已知有脓疱型银屑病病史的女性患者,出现皮肤弥漫性红斑和脱屑的亚急性发展,伴有与红皮病相符的剥脱区域。她病情不佳,需要住院,并使用含类固醇的湿敷、外用润肤剂、镇痛药和全身性免疫抑制剂进行积极治疗。

讨论

红皮病是一种皮肤科急症,其特征为超过90%的皮肤表面出现弥漫性红斑和脱屑,死亡率高达64%。它最初是一种临床诊断,需要迅速识别并积极治疗,以提高获得良好预后的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/a266495ad454/cpcem-8-388-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/080b31d94b49/cpcem-8-388-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/3a0c8b268fc7/cpcem-8-388-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/a266495ad454/cpcem-8-388-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/080b31d94b49/cpcem-8-388-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/3a0c8b268fc7/cpcem-8-388-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/061b/11661247/a266495ad454/cpcem-8-388-g003.jpg

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本文引用的文献

1
Pustular psoriasis: pathophysiology and current treatment perspectives.脓疱型银屑病:病理生理学与当前治疗观点
Psoriasis (Auckl). 2016 Sep 12;6:131-144. doi: 10.2147/PTT.S98954. eCollection 2016.
2
Erythroderma/exfoliative dermatitis: a synopsis.红皮病/剥脱性皮炎:概述
Int J Dermatol. 2004 Jan;43(1):39-47. doi: 10.1111/j.1365-4632.2004.01975.x.
3
Erythroderma.红皮病
Dermatol Clin. 2000 Jul;18(3):405-15. doi: 10.1016/s0733-8635(05)70189-3.
4
Erythroderma: a clinico-etiologic study of 90 cases.红皮病:90例临床病因学研究
Int J Dermatol. 1998 Feb;37(2):104-7. doi: 10.1046/j.1365-4362.1998.00228.x.