Bhattacharyya T K, Dayal V S
Ann Otol Rhinol Laryngol. 1985 Jan-Feb;94(1 Pt 1):75-80. doi: 10.1177/000348948509400116.
The spiral organ of the chinchilla was studied by the surface-preparation technique in four different age groups: 1 month, 6 months, 1 year, and 4 years, to assess age-related hair cell loss. Decrease in hair cell population is linearly related to age, and damage rate of outer hair cells is greater than that of inner hair cells. The mean percentage of damaged total outer hair cells was 0.60%, 1.16%, 1.71%, and 7.07% in animals in 1 month, 6 months, 1 year, and 4 years of age, respectively. Outer hair cell loss was greatest in the apex of the cochlea and, of these cells, the outermost row was the most affected. Damage to inner hair cells also increases with age. Age-related apical cochlear cell loss in the chinchilla is comparable to that observed in other laboratory animals.
采用表面制备技术，对四个不同年龄组（1个月、6个月、1岁和4岁）的龙猫螺旋器进行了研究，以评估与年龄相关的毛细胞损失。毛细胞数量的减少与年龄呈线性相关，外毛细胞的损伤率大于内毛细胞。1个月、6个月、1岁和4岁动物的受损外毛细胞总数的平均百分比分别为0.60%、1.16%、1.71%和7.07%。外毛细胞损失在耳蜗顶部最为严重，在这些细胞中，最外层的一排受影响最大。内毛细胞的损伤也随年龄增加。龙猫与年龄相关的耳蜗顶部细胞损失与在其他实验动物中观察到的情况相当。
