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门诊全关节置换术中血红蛋白的前瞻性无创监测

Prospective Noninvasive Hemoglobin Monitoring in the Outpatient Total Joint Arthroplasty Setting.

作者信息

Dugdale Evan M, Mallinger Benjamin D, Bedard Nicholas A, Couch Cory G, Mabry Tad M, Perry Kevin I, Sierra Rafael J, Taunton Michael J, Trousdale Robert T, Abdel Matthew P

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

J Bone Joint Surg Am. 2025 Feb 19;107(4):364-371. doi: 10.2106/JBJS.24.00438. Epub 2024 Dec 20.

Abstract

BACKGROUND

Total joint arthroplasty (TJA) is increasingly being performed as an outpatient (i.e., same-day discharge) procedure. Postoperatively, orthostatic hypotension or pain-related tachycardia can lead to concerns regarding the hemoglobin (Hgb) level of the patient prior to discharge. The purpose of this study was to prospectively assess the reliability and accuracy of, and patient and nurse satisfaction with, postoperative noninvasive hemoglobin (nHgb) monitoring compared with an invasive serum hemoglobin (iHgb) laboratory draw in the outpatient TJA setting.

METHODS

We prospectively enrolled 200 patients undergoing outpatient unilateral TJA, of whom 157 were ultimately included in our analysis (94 hips, 63 knees). Postoperatively, both nHgb and iHgb values were obtained at a mean of 36 minutes apart. Surveys were completed by patients and nurses. The strength of the agreement between the 2 Hgb monitoring methods was evaluated with use of the Bland-Altman 95% limits of agreement, concordance correlation coefficient (CCC), and intraclass correlation coefficient (ICC). Receiver operating characteristic curve analyses were performed to investigate the ability of nHgb monitoring to predict an iHgb of <11.2 g/dL (the 5th-percentile iHgb value).

RESULTS

The mean preoperative iHgb was 14.2 ± 1.1 g/dL. The mean postoperative iHgb and nHgb values were 13.3 ± 1.5 and 13.3 ± 1.2 g/dL, respectively. The Bland-Altman 95% limits of agreement were -3.2 and +3.1 g/dL, indicating that 95% of patients' iHgb values are expected to fall between these limits relative to the nHgb value of the patient. The CCC and ICC were both 0.33. An nHgb cutoff value of <12.7 g/dL had 100% sensitivity and 67% specificity for detecting an iHgb of <11.2 g/dL. Patients reported less pain with the nHgb test than with the iHgb test (mean pain score, 0.0 versus 1.8; p < 0.001), and 97% of patients preferred the nHgb test. Following the nHgb test, 73% of responding patients and 83% of responding nurses were "somewhat more reassured" to "significantly more reassured" about same-day discharge.

CONCLUSIONS

Routine nHgb testing can rapidly screen patients undergoing outpatient TJA for acute anemia prior to discharge. With an nHgb of <12.7 g/dL, there was perfect sensitivity and 67% specificity for detecting an iHgb of <11.2 g/dL. Most patients and nurses felt more reassured about same-day discharge after nHgb monitoring.

LEVEL OF EVIDENCE

Diagnostic Level II . See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

全关节置换术(TJA)越来越多地作为门诊手术(即当日出院)进行。术后,体位性低血压或疼痛相关的心动过速会引发对患者出院前血红蛋白(Hgb)水平的担忧。本研究的目的是前瞻性评估门诊TJA环境下术后无创血红蛋白(nHgb)监测与有创血清血红蛋白(iHgb)实验室检测相比的可靠性、准确性以及患者和护士的满意度。

方法

我们前瞻性纳入了200例行门诊单侧TJA的患者,其中157例最终纳入分析(94例髋关节,63例膝关节)。术后,nHgb和iHgb值平均间隔36分钟获取一次。患者和护士完成了调查问卷。使用Bland-Altman 95%一致性界限、一致性相关系数(CCC)和组内相关系数(ICC)评估两种Hgb监测方法之间的一致性强度。进行受试者操作特征曲线分析以研究nHgb监测预测iHgb<11.2 g/dL(第5百分位数iHgb值)的能力。

结果

术前iHgb的平均值为14.2±1.1 g/dL。术后iHgb和nHgb的平均值分别为13.3±1.5 g/dL和13.3±1.2 g/dL。Bland-Altman 95%一致性界限为-3.2和+3.1 g/dL,表明相对于患者的nHgb值,预计95%患者的iHgb值将落在这些界限之间。CCC和ICC均为0.33。nHgb临界值<12.7 g/dL检测iHgb<11.2 g/dL的敏感性为100%,特异性为67%。患者报告nHgb检测比iHgb检测疼痛程度轻(平均疼痛评分,0.0对1.8;p<0.001),97%的患者更喜欢nHgb检测。在进行nHgb检测后,73%的应答患者和83%的应答护士对当日出院“稍微更放心”至“显著更放心”。

结论

常规nHgb检测可在出院前快速筛查门诊TJA患者是否存在急性贫血。nHgb<12.7 g/dL时,检测iHgb<11.2 g/dL的敏感性为100%,特异性为67%。大多数患者和护士在nHgb监测后对当日出院更放心。

证据水平

诊断性II级。有关证据水平的完整描述,请参阅作者须知。

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