Anbarteh Rojin, Aftabi-Khadar Maryam, Hosseini-Hosseinabad Seyed Morteza, Seza Ashkan, Rahmani Fard Soheil, Minaeian Sara
Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
Department of Materials Science and Engineering, Iran University of Science and Technology, Tehran 1684613114, Iran.
Biomed Mater. 2025 Jan 6;20(1). doi: 10.1088/1748-605X/ada23a.
Different morphologies of graphitic carbon nitride (g-CN), including bulk g-CN(B-CN), ultrathin nanosheet g-CN(N-CN), and porous g-CN(P-CN) were synthesized through a facile one-step approach. They were then employed as efficient photocatalysts under visible light to degrade methylene blue and deactivate() and() bacteria. The synthesized powders were characterized using various industry standard techniques and field emission scanning electron microscopy (SEM) analysis successfully represented the various morphologies of g-CN. Furthermore, the antibacterial activities of synthesized samples were examined, and the results revealed that B-CN, N-CN, and P-CN powders could eliminate around 64%, 82%, and 99% ofunder visible light irradiation and about 30%, 56, and 67% in dark conditions. On the other hand, the bacterial reduction rate ofwas approximately 61%, 74%, and 99% for B-CN, N-CN, and P-CN powders under visible light irradiation and about 38%, 60%, and 77% in dark conditions. The SEM analysis revealed that P-CN causedandbacteria to rupture, completely separating their internal contents from the cell membrane. g-CNphotocatalytic antibacterial agents can be utilized as a unique potential solution for nosocomial infection management.
通过一种简便的一步法合成了不同形态的石墨相氮化碳（g-CN），包括块状g-CN（B-CN）、超薄纳米片g-CN（N-CN）和多孔g-CN（P-CN）。然后将它们用作可见光下高效的光催化剂，以降解亚甲基蓝并使（）和（）细菌失活。使用各种行业标准技术对合成的粉末进行了表征，场发射扫描电子显微镜（SEM）分析成功地呈现了g-CN的各种形态。此外，还对合成样品的抗菌活性进行了检测，结果表明，在可见光照射下，B-CN、N-CN和P-CN粉末可分别消除约64%、82%和99%的（），在黑暗条件下分别约为30%、56%和67%。另一方面，在可见光照射下，B-CN、N-CN和P-CN粉末对（）的细菌减少率分别约为61%、74%和99%，在黑暗条件下分别约为38%、60%和77%。SEM分析表明，P-CN导致（）和（）细菌破裂，使其内部物质与细胞膜完全分离。g-CN光催化抗菌剂可作为医院感染管理的一种独特潜在解决方案。
