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持续静脉输注利多卡因在治疗伴有2:1房室传导阻滞的先天性长QT综合征中的作用。

Contribution of continuous intravenous lidocaine in managing congenital long QT syndrome with 2:1 atrioventricular block.

作者信息

Nadeem Deebaj, Mohsin Muhammad, Qadir Faisal

机构信息

National Institute of Cardiovascular Diseases, Pakistan.

出版信息

Indian Pacing Electrophysiol J. 2025 Jan-Feb;25(1):47-49. doi: 10.1016/j.ipej.2024.12.003. Epub 2024 Dec 18.

Abstract

Congenital long QT syndrome (LQTS) is a rare hereditary cardiac disorder characterized by prolongation of the QT interval on electrocardiogram (ECG), predisposing affected individuals to life-threatening arrhythmias. We present a case of a newborn with congenital LQTS and 2:1 atrioventricular (AV) block who presented with bradycardia and QT prolongation. Continuous intravenous lidocaine infusion was initiated, because of hypoglycemia with beta-blockers, resulting in stabilization of AV conduction and prevention of malignant arrhythmias. This case underscores the potential utility of lidocaine as an adjunctive therapy in managing refractory arrhythmias in newborns with congenital LQTS and AV conduction abnormalities.

摘要

先天性长QT综合征(LQTS)是一种罕见的遗传性心脏疾病,其特征是心电图(ECG)上QT间期延长,使受影响个体易发生危及生命的心律失常。我们报告一例患有先天性LQTS和2:1房室(AV)传导阻滞的新生儿病例,该患儿表现为心动过缓和QT延长。由于使用β受体阻滞剂出现低血糖,开始持续静脉输注利多卡因,从而稳定了房室传导并预防了恶性心律失常。该病例强调了利多卡因作为辅助治疗手段在处理患有先天性LQTS和房室传导异常的新生儿难治性心律失常方面的潜在效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/11962303/ebd6f5f19ec8/gr1.jpg

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