Sheps S G, Schirger A, Spiekerman R E, Harman T R, O'Brien P C, Kleven M K, Kremer-Simpson K
Arch Intern Med. 1985 Jan;145(1):54-7.
Pindolol, a nonselective beta-adrenergic blocking drug, lowered systolic and diastolic BP equally well during once-daily and twice-daily dosage. Side effects were few. Absence of supine bradycardia distinguished this drug from other beta-adrenergic blockers and likely was attributable to the agent's intrinsic sympathomimetic activity. Blood pressure variability was less during therapy. Automatic indirect BP monitoring reliably confirmed office and home BP recordings and indicated good control throughout waking and sleeping periods.
吲哚洛尔，一种非选择性β-肾上腺素能阻滞剂，在每日一次和每日两次给药时，降低收缩压和舒张压的效果同样良好。副作用很少。无卧位心动过缓是该药物与其他β-肾上腺素能阻滞剂的区别所在，这可能归因于该药物的内在拟交感活性。治疗期间血压变异性较小。自动间接血压监测可靠地证实了诊室和家庭血压记录，并表明在整个清醒和睡眠期间血压控制良好。
