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原发性甲状旁腺功能亢进症中的棕色瘤最初被误诊为骨转移瘤和多发性巨细胞瘤:病例报告。

Brown tumors in primary hyperparathyroidism initially interpreted as bone metastases and multiple gigantocelular tumors: case report.

作者信息

Gladić Nenadić Vedrana, Punda Marija, Tabain Anita, Jukić Tomislav

机构信息

Department of Oncology and Nuclear Medicine, University Hospital Centre Sestre Milosrdnice, Zagreb, Croatia.

Department of Radiology and Nuclear Medicine, PET/CT Centre, Medikol Polyclinic, Zagreb, Croatia.

出版信息

EJNMMI Rep. 2024 Dec 21;8(1):40. doi: 10.1186/s41824-024-00229-1.

Abstract

Brown tumors or osteitis fibrosa cystica are a rare bone metabolism disorder that may mimic cancer metastasis. It represents a late manifestation of prolonged and mostly unrecognized hyperparathyroidism. In this case report we present a 44-year-old female patient with multiple lesions detected on bone scintigraphy and F- FDG-PET/CT, initially interpreted as a bone metastatic disease, rather than multiple gigantocellular bone tumors. Additionally, the presented case emphasizes the importance of a multidisciplinary approach in diagnosing brown tumors as part of hyperparathyroidism, and the treatment decision.

摘要

棕色瘤或纤维囊性骨炎是一种罕见的骨代谢紊乱疾病,可能会被误诊为癌症转移。它是长期存在且大多未被识别的甲状旁腺功能亢进的晚期表现。在本病例报告中,我们介绍了一名44岁女性患者,其在骨闪烁显像和F-FDG-PET/CT检查中发现多处病变,最初被误诊为骨转移性疾病,而非多发性巨细胞骨肿瘤。此外,该病例强调了多学科方法在诊断作为甲状旁腺功能亢进一部分的棕色瘤以及治疗决策中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4b6/11662108/5d38bfeeeedb/41824_2024_229_Fig1_HTML.jpg

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