Duyck Julien, Spincemaille Katrien, Verfaillie Jan, Meert Caressa, Muylle Kristoff
Department of Nuclear Medicine, AZ Delta, Roeselare, Belgium.
, Beselare, Belgium.
Eur J Hybrid Imaging. 2023 Jun 8;7(1):10. doi: 10.1186/s41824-023-00168-3.
Brown tumors or osteitis fibrosa cystica has become a rare presentation of primary hyperparathyroidism in up-to-date clinical practice. Here, we describe a case of longstanding untreated hyperparathyroidism presenting itself with brown tumors in a 65-year-old patient. During the diagnostic work-up of this patient, bone SPECT/CT and F-FDG-PET/CT revealed multiple widespread osteolytic lesions. Differentiating from other bone tumors such as multiple myeloma is challenging. In this case, the final diagnosis was made by integrating the medical history, biochemical diagnosis of primary hyperparathyroidism, pathological findings and medical imaging.
棕色瘤或纤维囊性骨炎在当今临床实践中已成为原发性甲状旁腺功能亢进的罕见表现。在此，我们描述一例65岁长期未治疗的甲状旁腺功能亢进患者，其表现为棕色瘤。在对该患者的诊断检查过程中，骨SPECT/CT和F-FDG-PET/CT显示多处广泛的溶骨性病变。与其他骨肿瘤如多发性骨髓瘤进行鉴别具有挑战性。在本病例中，通过综合病史、原发性甲状旁腺功能亢进的生化诊断、病理结果和医学影像做出了最终诊断。
