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解决注射吸毒者中丙型肝炎治疗起始社会障碍的实用解决方案:一项定性研究

Practical solutions to resolve social barriers to hepatitis C treatment initiation among people who inject drugs: a qualitative study.

作者信息

Aung Phyo, Hellard Margaret, Dietze Paul, Petrovic Bek, Higgs Peter, Stoové Mark

机构信息

Disease Elimination Program, Burnet Institute, 85 Commercial Road, Melbourne, VIC, 3004, Australia.

Department of Epidemiology and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.

出版信息

Harm Reduct J. 2024 Dec 20;21(1):221. doi: 10.1186/s12954-024-01136-1.

Abstract

BACKGROUND

We aimed to identify motivators for people who inject drugs to pursue treatment for hepatitis C virus (HCV) infection and uncover opportunities that could make treatment more appealing.

METHODS

Between November 2023 and January 2024, we conducted semi-structured interviews with 15 HCV RNA-positive individuals with a history of injecting drug use and self-reported as either untreated or treated but delayed treatment for more than 6 months. Thematic and framework data analysis was employed and interpreted using the Capability, Opportunity and Motivation (COM-B) framework of behaviour change.

RESULTS

The findings suggest that a combination of stability through secure housing, mental readiness and overcoming drug dependence supported by OAT (Capability), accessible and convenient healthcare like mobile outreach services coupled with financial incentives (Opportunity), and supportive relationships (Motivation) could serve to help people who inject drugs take up HCV treatment.

CONCLUSION

Alcohol and other drug and primary care services for people who use drugs should adopt person-centred approaches and recognise the gradual nature of behavioural change to foster empathy and supportive relationships to promote engagement in HCV care. Additionally, integrating HCV treatment with mobile outreach services and providing practical assistance, such as housing and financial incentives, are critical to ensuring that individuals remain engaged in HCV care.

摘要

背景

我们旨在确定注射吸毒者寻求丙型肝炎病毒(HCV)感染治疗的动机,并发现可使治疗更具吸引力的机会。

方法

在2023年11月至2024年1月期间,我们对15名HCV RNA呈阳性且有注射吸毒史的个体进行了半结构化访谈,这些个体自我报告为未接受治疗或已接受治疗但延迟治疗超过6个月。采用主题和框架数据分析,并使用行为改变的能力、机会和动机(COM-B)框架进行解释。

结果

研究结果表明,通过保障性住房实现稳定、心理准备以及在阿片类药物替代治疗(OAT)支持下克服药物依赖(能力),像移动外展服务这样便捷可及的医疗保健并辅以经济激励措施(机会),以及支持性的人际关系(动机)相结合,有助于注射吸毒者接受HCV治疗。

结论

针对吸毒者的酒精和其他药物以及初级保健服务应采用以患者为中心的方法,认识到行为改变的渐进性,以培养同理心和支持性的人际关系,促进参与HCV护理。此外,将HCV治疗与移动外展服务相结合,并提供诸如住房和经济激励等实际援助,对于确保个体持续参与HCV护理至关重要。

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