George Catherine Mariam, Dabbagh Armaghan, Unger Janelle, Babatunde Folarin, MacDermid Joy C
Faculty of Health Sciences, University of Western Ontario, London, ON, Canada.
Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, ON, Canada.
Qual Life Res. 2025 Apr;34(4):893-912. doi: 10.1007/s11136-024-03877-9. Epub 2024 Dec 21.
Patient Reported Outcome Measures (PROMs) are used widely to collect patient perspectives on their Health-Related Quality of Life (HRQoL) after stroke. Existing reviews on PROMs typically report the psychometric properties but rarely focus on the content validity. We performed a structured review of the content of items of stroke-specific HRQoL outcomes.
We searched four databases using a combination of terms (Stroke, HRQoL, PROMs) to choose the three most frequently used stroke-specific HRQoL-related PROMs. Two raters independently linked the items of the Stroke Impact Scale, Stroke Specific Quality of Life and the Stroke and Aphasia Quality of Life to the International Classification of Functioning, Disability and Health (ICF) and Item Perspective Classification (IPC). We compared the ICF codes to the ICF Core Sets for Stroke and calculated ICF linkage indicators.
More than 75% of the content for all three PROMs is represented in the Comprehensive Stroke Core Set, indicating the universality and validity of the content of these PROMs. All three PROMs represent the content of the ICF Core Sets for Stroke to a similar extent. Most items use an Intensity response option and have a Descriptive perspective. On the IPC framework, most items have a Rational appraisal type and represent the Biological domain.
Clinicians and researchers should use patient goals as a reference to choose the appropriate PROM. A deeper understanding of the content of PROMs can help clinicians and researchers make informed decisions on which HRQoL outcomes to use among people following stroke.
患者报告结局测量指标（PROMs）被广泛用于收集患者对中风后健康相关生活质量（HRQoL）的看法。现有的关于PROMs的综述通常报告其心理测量特性，但很少关注内容效度。我们对中风特异性HRQoL结局指标的项目内容进行了结构化综述。
我们使用（中风、HRQoL、PROMs）等术语组合在四个数据库中进行检索，以选择三个最常用的与中风特异性HRQoL相关的PROMs。两名评估者独立地将中风影响量表、中风特异性生活质量量表和中风与失语症生活质量量表的项目与国际功能、残疾和健康分类（ICF）及项目视角分类（IPC）进行关联。我们将ICF编码与中风ICF核心集进行比较，并计算ICF关联指标。
所有三个PROMs超过75%的内容都体现在综合中风核心集中，这表明这些PROMs内容的普遍性和有效性。所有三个PROMs在相似程度上体现了中风ICF核心集的内容。大多数项目使用强度反应选项，且具有描述性视角。在IPC框架上，大多数项目具有理性评估类型，并代表生物学领域。
临床医生和研究人员应将患者目标作为选择合适PROM的参考。对PROMs内容的更深入理解有助于临床医生和研究人员就是否在中风患者中使用HRQoL结局指标做出明智的决策。
