Ishiguro-Tanaka Noriko, Kitagawa Funa, Akima Hiroshi
Research Center of Health, Physical Fitness and Sports, Nagoya University, Nagoya, Japan.
Graduate School of Education and Human Development, Nagoya University, Nagoya, Japan.
Clin Physiol Funct Imaging. 2025 Jan;45(1). doi: 10.1111/cpf.12922.
The present study examined the relationships between trunk tissue distribution, metabolic risk factors, and physical performance in young Japanese individuals using cross-sectional and longitudinal analyses. Thirty-six healthy Japanese men (n = 20, body mass index [BMI]: 20.8 ± 2.0 kg/m) and women (n = 16, BMI: 19.6 ± 2.0 kg/m) aged 20-26 years old visited our laboratory twice with an interval of 1 year. The thicknesses of skeletal muscle (MT), subcutaneous adipose tissue (SCAT), and the intra-abdominal cavity (IAT) were assessed by ultrasound imaging and adjusted by body mass (BM). Blood properties related to hepatic function or metabolic syndrome, brachial-ankle pulse wave velocity, hand grip strength, two-step-length/height scores, and sit-and-reach test scores were also measured. As a result of the cross-sectional analysis, significant relationships were observed between SCAT/BM and indices of glucose metabolism (HOMA-IR and QUICKI) in men (r = 0.513 and -0.583), and between IAT/BM and fasting blood glucose in women (r = 0.524). Longitudinal analyses of women showed that changes (%) in IAT and MT/IAT correlated with % changes in the indices of hepatic function (AST) and glucose metabolism (HOMA-IR and HOMA-β) (r = -0.673 to 0.686). Significant correlations were also observed between MT/IAT and walking ability (two-step-length/height) in cross-sectional and longitudinal analyses of men (r = 0.463 and 0.525). In conclusion, the trunk tissue distribution could be used to detect the early symptoms of metabolic risks and declines in physical performance in young men and women.
本研究采用横断面分析和纵向分析，探讨了日本年轻人群体中躯干组织分布、代谢风险因素与身体机能之间的关系。36名年龄在20 - 26岁的健康日本男性（n = 20，体重指数[BMI]：20.8±2.0kg/m²）和女性（n = 16，BMI：19.6±2.0kg/m²），间隔1年两次到访我们的实验室。通过超声成像评估骨骼肌（MT）、皮下脂肪组织（SCAT）和腹腔内（IAT）的厚度，并根据体重（BM）进行调整。还测量了与肝功能或代谢综合征相关的血液指标、臂踝脉搏波速度、握力、两步长/身高得分以及坐位体前屈测试得分。横断面分析结果显示，男性中SCAT/BM与葡萄糖代谢指标（HOMA-IR和QUICKI）之间存在显著相关性（r = 0.513和 -0.583），女性中IAT/BM与空腹血糖之间存在显著相关性（r = 0.524）。女性的纵向分析表明，IAT和MT/IAT的变化（%）与肝功能指标（AST）和葡萄糖代谢指标（HOMA-IR和HOMA-β）的变化（%）相关（r = -0.673至0.686）。在男性的横断面和纵向分析中，MT/IAT与步行能力（两步长/身高）之间也观察到显著相关性（r = 0.463和0.525）。总之，躯干组织分布可用于检测年轻男性和女性代谢风险的早期症状以及身体机能的下降。
