根据睡眠呼吸暂停状态的糖尿病前期患病率。

Prevalence of prediabetes according to sleep apnea status.

作者信息

Um Yoo Jin, Kim Ho, Sung Joohon, Um Yoo Hyun, Cho Sung-Il

机构信息

Department of Family Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, South Korea.

Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, South Korea; Institute of Health and Environment, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.

出版信息

Prim Care Diabetes. 2025 Feb;19(1):61-65. doi: 10.1016/j.pcd.2024.12.004. Epub 2024 Dec 21.

DOI:10.1016/j.pcd.2024.12.004

PMID:39710550

Abstract

AIM

The association between obstructive sleep apnea (OSA) and prediabetes using the STOP-Bang questionnaire remains unknown. We aimed to investigate the prevalence of prediabetes among people based on their sleep apnea status.

METHODS

This cross-sectional study included 10131 Korean adults without diabetes with information of STOP-Bang scores, drawn from the dataset of the Korea National Health and Nutrition Examination Survey 2019-2021. Prediabetes was defined in three subsets: only by fasting blood glucose (FBG) (FBG 100-125 mg/dL, HbA1c <5.7 %), only by HbA1c (FBG <100 mg/dL, HbA1c 5.7-6.4 %) or by both. We used multivariable logistic regression to assess the odds ratio (OR) and 95 % confidence intervals (CIs) for prediabetes.

RESULTS

A total of 3828 subjects reported a STOP-Bang score of ≥ 3, which shows increased risk of OSA. Multivariable-adjusted OR (95 % CI) showed that a STOP-Bang score ≥ 3 was associated with prediabetes meeting both FBG and HbA1c criteria (OR 1.06; 95 % CI 1.01-1.12). This association was statistically significant among women, particularly postmenopausal women (OR 1.20, 95 % CI 1.10-1.30; OR 1.21, 95 % CI 1.11-1.32, respectively).

CONCLUSION

In Korean general population, a significant correlation between higher OSA risk and prediabetes was observed, especially in postmenopausal women.

摘要

目的

使用STOP-Bang问卷评估阻塞性睡眠呼吸暂停（OSA）与糖尿病前期之间的关联仍不明确。我们旨在根据睡眠呼吸暂停状态调查人群中糖尿病前期的患病率。

方法

这项横断面研究纳入了10131名无糖尿病的韩国成年人，这些人来自2019 - 2021年韩国国家健康与营养检查调查数据集，有STOP-Bang评分信息。糖尿病前期在三个亚组中定义：仅依据空腹血糖（FBG）（FBG 100 - 125mg/dL，糖化血红蛋白[HbA1c] <5.7%）、仅依据HbA1c（FBG <100mg/dL，HbA1c 5.7 - 6.4%）或两者兼有。我们使用多变量逻辑回归来评估糖尿病前期的比值比（OR）和95%置信区间（CI）。

结果

共有3828名受试者报告STOP-Bang评分≥3，这表明OSA风险增加。多变量调整后的OR（95% CI）显示，STOP-Bang评分≥3与符合FBG和HbA1c标准的糖尿病前期相关（OR 1.06；95% CI 1.01 - 1.12）。这种关联在女性中具有统计学意义，尤其是绝经后女性（分别为OR 1.20，95% CI 1.10 - 1.30；OR 1.21，95% CI 1.11 - 1.32）。