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开放性胫骨骨折的感染风险及从外固定转换为确定性固定的时间

Risk of infection and conversion time from external to definitive fixation in open tibial fracture.

作者信息

Aljuhani Wazzan S, Alshabi Yasir A, Alanazi Abdullah M, Alothri Meshal A, Almutairi Saleh A, Aljaafri Ziad A, Alzahrani Abdullah M

机构信息

Department of Orthopedic Surgery, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

出版信息

J Orthop Surg Res. 2024 Dec 23;19(1):867. doi: 10.1186/s13018-024-05350-2.

Abstract

BACKGROUND

An open fracture of the tibia is one of the most common and dangerous type of open fractures. In the management of these injuries, the primary focus is on reducing the infection rate, as this is crucial for achieving the best clinical outcomes. This study aims to explore how provisional external fixation duration influences the rates of infection and union in open tibial shaft fractures.

METHODS

A retrospective study with a total of 55 patients who received temporary external fixation. Groups A (less than 12 days), B (12-24), C (25-36), and D (more than 36) were the four groups into which they were split according to the conversion time.

RESULTS

12.8%, 18.2%, 50%, and 100% of the infections were found in Groups A, B, C, and D, respectively. Significant (P < 0.05) differences were found throughout the four groups. The conversion time from external to definitive fixation was found to have a relationship with the occurrence of an infection (P = 0.004). A higher prevalence of infection was observed over time. However, no association was observed between infection and antibiotic duration or initial debridement time (P = 0.689 and P = 0.963, respectively).

CONCLUSIONS

Results of this study demonstrate that the likelihood of infection increases when the change from external fixation to definitive internal fixation is delayed. Therefore, it is important to convert to definitive internal fixation immediately when the local and general conditions are favorable for doing so.

摘要

背景

胫骨开放性骨折是最常见且危险的开放性骨折类型之一。在处理这些损伤时,主要关注点在于降低感染率,因为这对于取得最佳临床结果至关重要。本研究旨在探讨临时外固定时间对胫骨干开放性骨折的感染率和骨愈合率有何影响。

方法

对总共55例接受临时外固定的患者进行回顾性研究。根据转换时间将他们分为四组:A组(少于12天)、B组(12 - 24天)、C组(25 - 36天)和D组(超过36天)。

结果

A组、B组、C组和D组的感染率分别为12.8%、18.2%、50%和100%。四组之间存在显著(P < 0.05)差异。发现从外固定转换为确定性固定的时间与感染的发生有关(P = 0.004)。随着时间推移,感染发生率更高。然而,未观察到感染与抗生素使用时长或初次清创时间之间存在关联(分别为P = 0.689和P = 0.963)。

结论

本研究结果表明,从外固定转换为确定性内固定的时间延迟会增加感染的可能性。因此,当局部和全身情况有利于进行时,立即转换为确定性内固定很重要。

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