Khasawneh Hala, O'Brien Ciara, Czeyda-Pommersheim Ferenc, Qayyum Aliya, Miller Frank H, Arif Tiwari Hina, Paspulati Raj Mohan, Kierans Andrea S
The University of Texas Southwestern Medical Center, Dallas, USA.
University of Toronto, Toronto, Canada.
Abdom Radiol (NY). 2024 Dec 23. doi: 10.1007/s00261-024-04749-z.
Cholangiocarcinoma (CCA) is the second most common primary malignancy of the hepatobiliary system and presents as a heterogeneous disease with three distinct morphological subtypes: mass-forming, periductal-infiltrating, and intraductal-growing, each characterized by distinguishing imaging features. Accurate diagnosis of CCA is challenging due to the overlap of imaging findings with a broad range of benign and malignant conditions. Therefore, it is essential for radiologists to recognize these mimickers and offer a reasonable differential diagnosis, as this has a significant impact on patient management. Although histopathological confirmation is often required for a definitive diagnosis, understanding specific imaging characteristics that differentiate CCA from its mimickers is crucial. This article highlights a variety of benign and malignant conditions that resemble CCA on imaging, emphasizing features that enhance diagnostic accuracy in clinical practice.
胆管癌（CCA）是肝胆系统第二常见的原发性恶性肿瘤，是一种具有三种不同形态学亚型的异质性疾病：肿块型、胆管周围浸润型和管内生长型，每种亚型都有其独特的影像学特征。由于CCA的影像学表现与多种良性和恶性疾病存在重叠，因此准确诊断具有挑战性。因此，放射科医生识别这些相似疾病并提供合理的鉴别诊断至关重要，因为这对患者的治疗管理有重大影响。虽然明确诊断通常需要组织病理学证实，但了解将CCA与其相似疾病区分开来的特定影像学特征至关重要。本文重点介绍了多种在影像学上与CCA相似的良性和恶性疾病，强调了有助于提高临床实践中诊断准确性的特征。
