Goodman Georgia R, Overstreet Demario S, Wilson Jenna M, O'Cleirigh Conall, Boyer Edward W, Meints Samantha M, Taylor S Wade, Mayer Kenneth H, Schreiber Kristin L, Chai Peter R
The Fenway Institute, Fenway Health, Boston, Massachusetts, USA.
Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
AIDS Res Hum Retroviruses. 2025 May;41(5):263-273. doi: 10.1089/aid.2024.0072. Epub 2024 Dec 23.
Chronic pain can be complicated by problematic opioid use, which may decrease engagement in care and HIV medication adherence. Pain-related anxiety and catastrophic thinking augment pain severity and interference while driving increased substance use. The acceptability and effect of a music-based smartphone application on negative affect and catastrophic thinking were evaluated in a mixed-methods study among persons living with HIV (PWH) with problematic opioid use and chronic pain. Participants ( = 16) completed a 10-min music listening session, quantitative assessment and qualitative interview. Paired sample -tests compared pre- and post-test scores of negative affect (Profile of Mood States-Short Form) and pain catastrophizing (Situational Pain Catastrophizing Scale) before and after music. Qualitative data were analyzed using within-case, across-case analysis. Negative affect significantly decreased after the music listening session (pre 8.3 ± 6.7 vs. post 1.8 ± 2.6; = .0003), as did pain catastrophizing (pre 8.5 ± 4.3 vs. post 2.5 ± 3.4; < .0001). Qualitatively, participants ( = 14) viewed the app-based music listening session as acceptable and potentially useful as an intervention or adjuvant for pain management and reduction of opioid use. Overall, a brief exposure to a novel music app produced significant improvements in negative affect and pain-related catastrophic thoughts among PWH with problematic opioid use and chronic pain. Future work should further explore the effects of music on pain and the use of illicit substances more broadly in this population.
慢性疼痛可能因阿片类药物使用问题而复杂化，这可能会降低对治疗的参与度以及艾滋病毒药物的依从性。与疼痛相关的焦虑和灾难化思维会加剧疼痛的严重程度和干扰，同时导致物质使用增加。在一项混合方法研究中，对一款基于音乐的智能手机应用程序对艾滋病毒感染者（PWH）中使用阿片类药物存在问题且患有慢性疼痛者的负面影响和灾难化思维的可接受性及效果进行了评估。参与者（n = 16）完成了一次10分钟的音乐聆听环节、定量评估和定性访谈。配对样本t检验比较了聆听音乐前后负面情绪（简式情绪状态量表）和疼痛灾难化（情境疼痛灾难化量表）的测试前和测试后分数。定性数据采用个案内、跨案例分析进行分析。聆听音乐环节后，负面影响显著降低（聆听前8.3±6.7 vs. 聆听后1.8±2.6；p = . .0003），疼痛灾难化程度也显著降低（聆听前8.5±4.3 vs. 聆听后2.5±3.4；p < .0001）。定性方面，参与者（n = 14）认为基于应用程序的音乐聆听环节是可接受的，并且作为疼痛管理和减少阿片类药物使用的干预措施或辅助手段可能有用。总体而言，对于使用阿片类药物存在问题且患有慢性疼痛的艾滋病毒感染者，短暂接触一款新颖的音乐应用程序能显著改善负面影响和与疼痛相关的灾难化思维。未来的工作应进一步探索音乐对该人群疼痛及非法物质使用的更广泛影响。
