Chai Peter R, Schwartz Emily, Hasdianda Mohammad Adrian, Azizoddin Desiree R, Kikut Anna, Jambaulikar Guruprasad D, Edwards Robert R, Boyer Edward W, Schreiber Kristin L
Division of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, MA, United States.
J Med Internet Res. 2020 May 20;22(5):e18537. doi: 10.2196/18537.
Emergency physicians face the challenge of relieving acute pain daily. While opioids are a potent treatment for pain, the opioid epidemic has ignited a search for nonopioid analgesic alternatives that may decrease the dose or duration of opioid exposure. While behavioral therapies and complementary medicine are effective, they are difficult to deploy in the emergency department. Music is a potential adjunctive therapy that has demonstrated effectiveness in managing pain.
Our objective was to understand the feasibility and potential for an effect of a novel music app to address acute pain and anxiety in patients admitted to an emergency department observation unit.
This prospective cohort study enrolled patients admitted to an emergency department observation unit with pain who had received orders for opioids. We gathered baseline pain and psychosocial characteristics including anxiety, sleep disturbance, and pain catastrophizing using validated questionnaires. Participants received a smartphone-based music intervention and listened to the music in either a supervised (research assistant-delivered music session 3 times during their stay) or unsupervised manner (music used ad lib by participant). The app collected premusic and postmusic pain and anxiety scores, and participants provided qualitative feedback regarding acceptability of operating the music intervention.
We enrolled 81 participants and randomly assigned 38 to an unsupervised and 43 to a supervised group. Mean pain in both groups was 6.1 (1.8) out of a possible score of 10. A total of 43 (53%) reported previous use of music apps at home. We observed an overall modest but significant decrease in pain (mean difference -0.81, 95% CI -0.45 to -1.16) and anxiety (mean difference -0.72, 95% CI -0.33 to -1.12) after music sessions. Reduction of pain and anxiety varied substantially among participants. Individuals with higher baseline pain, catastrophizing (about pain), or anxiety reported greater relief. Changes in pain were correlated to changes in anxiety (Pearson ρ=0.3, P=.02) but did not vary between supervised and unsupervised groups. Upon conclusion of the study, 46/62 (74%) reported they liked the music intervention, 57/62 (92%) reported the app was easy to use, and 49/62 (79%) reported they would be willing to use the music intervention at home.
A smartphone-based music intervention decreased pain and anxiety among patients in an emergency department observation unit, with no difference between supervised and unsupervised use. Individuals reporting the greatest reduction in pain after music sessions included those scoring highest on baseline assessment of catastrophic thinking, suggesting there may be specific patient populations that may benefit more from using music as an analgesic adjunct in the emergency department. Qualitative feedback suggested that this intervention was feasible and acceptable by emergency department patients.
急诊医生每天都面临着缓解急性疼痛的挑战。虽然阿片类药物是治疗疼痛的有效药物,但阿片类药物的泛滥引发了对非阿片类镇痛替代方案的探索,这些替代方案可能会减少阿片类药物的使用剂量或时长。虽然行为疗法和补充医学有效,但它们在急诊科难以实施。音乐是一种潜在的辅助疗法,已证明在疼痛管理方面有效。
我们的目的是了解一款新型音乐应用程序在急诊科观察病房患者中缓解急性疼痛和焦虑的可行性及效果潜力。
这项前瞻性队列研究纳入了因疼痛入住急诊科观察病房且已收到阿片类药物医嘱的患者。我们使用经过验证的问卷收集了基线疼痛和心理社会特征,包括焦虑、睡眠障碍和疼痛灾难化。参与者接受了基于智能手机的音乐干预,并以监督(研究助理在其住院期间进行3次音乐播放)或非监督方式(参与者随意使用音乐)收听音乐。该应用程序收集了音乐播放前和播放后的疼痛及焦虑评分,参与者提供了关于操作音乐干预可接受性的定性反馈。
我们招募了81名参与者,随机将38名分配到非监督组,43名分配到监督组。两组的平均疼痛评分为6.1(1.8)(满分10分)。共有43名(53%)报告此前在家中使用过音乐应用程序。我们观察到音乐播放后疼痛(平均差值 -0.81,95%可信区间 -0.45至 -1.16)和焦虑(平均差值 -0.72,95%可信区间 -0.33至 -1.12)总体有适度但显著的降低。参与者之间疼痛和焦虑的减轻程度差异很大。基线疼痛、灾难化(关于疼痛)或焦虑程度较高的个体疼痛缓解更明显。疼痛变化与焦虑变化相关(Pearson ρ = 0.3,P = 0.02),但在监督组和非监督组之间没有差异。研究结束时,46/62(74%)报告他们喜欢音乐干预,57/62(92%)报告该应用程序易于使用,49/62(79%)报告他们愿意在家中使用音乐干预。
基于智能手机的音乐干预降低了急诊科观察病房患者的疼痛和焦虑,监督使用和非监督使用之间没有差异。音乐播放后疼痛减轻最明显的个体包括在灾难化思维基线评估中得分最高的那些人,这表明可能有特定的患者群体在急诊科使用音乐作为镇痛辅助手段时可能受益更多。定性反馈表明这种干预对急诊科患者来说是可行且可接受的。