女性军事航空军官子女的新生儿健康风险。

Neonatal Health Risks Among Children of Female Military Aviation Officers.

作者信息

Stark Christopher M, Sorensen Ian S, Royall Matthew, Dorr Madeline, Brown Jill, Dobson Nicole, Salzman Sandra, Susi Apryl, Hisle-Gorman Elizabeth, Huggins Brian H, Nylund Cade M

出版信息

Aerosp Med Hum Perform. 2024 Nov;95(11):815-820. doi: 10.3357/AMHP.6417.2024.

DOI:10.3357/AMHP.6417.2024

PMID:39711346

Abstract

INTRODUCTION

The aviation occupational environment may expose a developing fetus to intermittent hypoxia, high gravitational force, toxic materials, loud noise, high frequency vibrations, and galactic cosmic radiation. These exposures in animal models are associated with adverse neonatal outcomes. We sought to investigate whether a maternal military aviation career was associated with adverse neonatal health outcomes.

METHODS

We performed a retrospective cohort study of female officer's children born in the Military Health System from October 2002 to December 2019. Female fixed-wing aviation officers were identified by the presence of an aviation occupation code prior to birth. Adverse neonatal outcomes were identified by International Classification of Diseases codes in in-patient medical records. Binomial regression was used to estimate the adjusted relative risk (aRR) of neonatal health outcomes.

RESULTS

We identified 27,033 eligible births, with 1144 children born to female fixed-wing aviation officers and 25,889 to female nonaviation officers. Children of fixed-wing aviation officers had a significantly lower adjusted risk of overall neonatal growth abnormalities compared to children of nonaviation officers [aRR 0.74 (95% Confidence Interval 0.57-0.99)], but did not have significant differences in low birth weight [aRR 0.78 (0.56-1.10)] or small for gestational age [aRR 0.72 (0.46-1.10)] diagnoses. There were no statistically significant adverse neonatal outcomes.

DISCUSSION

Children of female military fixed-wing aviation officers were at decreased risk of neonatal growth abnormalities compared to children of nonaviation officers and had no significant adverse neonatal health outcomes. Further research is needed to determine how flight impacts neonatal health outcomes. Stark CM, Sorensen IS, Royall M, Dorr M, Brown J, Dobson N, Salzman S, Susi A, Hisle-Gorman E, Huggins BH, Nylund CM. Neonatal health risks among children of female military aviation officers. Aerosp Med Hum Perform. 2024; 95(11):815-820.

摘要

引言

航空职业环境可能会使发育中的胎儿暴露于间歇性缺氧、高重力、有毒物质、噪音、高频振动和银河宇宙辐射中。在动物模型中，这些暴露与不良的新生儿结局相关。我们试图调查母亲的军事航空职业是否与不良的新生儿健康结局有关。

方法

我们对2002年10月至2019年12月在军事卫生系统出生的女性军官子女进行了一项回顾性队列研究。通过出生前的航空职业代码确定女性固定翼航空军官。通过住院病历中的国际疾病分类代码确定不良新生儿结局。使用二项式回归来估计新生儿健康结局的调整相对风险（aRR）。

结果

我们确定了27033例符合条件的出生病例，其中1144名儿童为女性固定翼航空军官所生，25889名儿童为女性非航空军官所生。与非航空军官的子女相比，固定翼航空军官的子女总体新生儿生长异常的调整风险显著更低[aRR 0.74（95%置信区间0.57 - 0.99）]，但在低出生体重[aRR 0.78（0.56 - 1.10）]或小于胎龄[aRR 0.72（0.46 - 1.10）]诊断方面没有显著差异。没有统计学上显著的不良新生儿结局。

讨论

与非航空军官的子女相比，女性军事固定翼航空军官的子女新生儿生长异常的风险降低，且没有显著的不良新生儿健康结局。需要进一步研究以确定飞行如何影响新生儿健康结局。斯塔克CM、索伦森IS、罗亚尔M、多尔M、布朗J、多布森N、萨尔兹曼S、苏西A、希斯尔 - 戈尔曼E、哈金斯BH、尼伦德CM。女性军事航空军官子女的新生儿健康风险。航空航天医学与人类表现。2024；95（11）：815 - 820。