Hippocampal Inhibitory Neuron Loss Is Epileptogenic But Not Likely a Sole Cause of Mesial Temporal Lobe Epilepsy (MTLE).
作者信息
Goodman Jeffrey H
机构信息
Department of Developmental Neurobiology.
NYS Institute for Basic Research in Developmental Disabilities.
出版信息
Epilepsy Curr. 2024 Dec 12;25(1):61-63. doi: 10.1177/15357597241303611. eCollection 2025 Jan-Feb.
Abstract
摘要
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本文引用的文献
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Transient Seizure Clusters and Epileptiform Activity Following Widespread Bilateral Hippocampal Interneuron Ablation.广泛双侧海马中间神经元消融后的短暂性癫痫发作簇和癫痫样活动
eNeuro. 2024 Apr 22;11(4). doi: 10.1523/ENEURO.0317-23.2024. Print 2024 Apr.
2
Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats.稳定型神经激肽 1-saporin 靶向海马 GABA 神经元消融导致大鼠海马硬化和慢性癫痫。
Epilepsia. 2019 May;60(5):e52-e57. doi: 10.1111/epi.14723. Epub 2019 Apr 8.
3
Targeted Interneuron Ablation in the Mouse Hippocampus Can Cause Spontaneous Recurrent Seizures.在小鼠海马区进行靶向神经元消融会导致自发性复发性癫痫。
eNeuro. 2017 Jul 21;4(4). doi: 10.1523/ENEURO.0130-17.2017. eCollection 2017 Jul-Aug.
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Seizure frequency correlates with loss of dentate gyrus GABAergic neurons in a mouse model of temporal lobe epilepsy.在颞叶癫痫小鼠模型中，癫痫发作频率与齿状回GABA能神经元的丧失相关。
J Comp Neurol. 2017 Aug 1;525(11):2592-2610. doi: 10.1002/cne.24226. Epub 2017 May 11.
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Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy.消融新生成的海马颗粒细胞对癫痫具有疾病修饰作用。
J Neurosci. 2016 Oct 26;36(43):11013-11023. doi: 10.1523/JNEUROSCI.1371-16.2016.
6
Functional regulation of the dentate gyrus by GABA-mediated inhibition.GABA介导的抑制对齿状回的功能调节
Prog Brain Res. 2007;163:235-43. doi: 10.1016/S0079-6123(07)63014-3.
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Reduced inhibition of dentate granule cells in a model of temporal lobe epilepsy.颞叶癫痫模型中齿状颗粒细胞抑制作用减弱。
J Neurosci. 2003 Mar 15;23(6):2440-52. doi: 10.1523/JNEUROSCI.23-06-02440.2003.
8
Sustained electrical stimulation of the perforant path duplicates kainate-induced electrophysiological effects and hippocampal damage in rats.对大鼠的穿通通路进行持续电刺激可重现红藻氨酸诱导的电生理效应及海马损伤。
Neurosci Lett. 1981 Jul 17;24(3):279-84. doi: 10.1016/0304-3940(81)90171-3.
9
Epilepsy and the temporal lobes. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes.癫痫与颞叶。一项关于癫痫患者大脑的临床、脑电图及神经病理学研究，特别涉及颞叶。
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Electroencephalogr Clin Neurophysiol. 1972 Mar;32(3):281-94. doi: 10.1016/0013-4694(72)90177-0.
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