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主动脉夹层合并肠系膜灌注不良综合征表现为肝缺血:一例报告及文献综述

Aortic Dissection Complicated by Mesenteric Malperfusion Syndrome Presenting As Hepatic Ischemia: A Case Report and Literature Review.

作者信息

Mahamud Bashir, Sarwar Shoayeb, Eltayieb Lina, Mahdi Hussameldin, Mlawa Gideon

机构信息

Acute Medicine, Barking, Havering and Redbridge National Health Service (NHS) Hospital Trust, London, GBR.

Internal Medicine, Barking, Havering and Redbridge National Health Service (NHS) Hospital Trust, London, GBR.

出版信息

Cureus. 2024 Nov 21;16(11):e74139. doi: 10.7759/cureus.74139. eCollection 2024 Nov.

Abstract

Aortic dissection (AD) is a medical emergency that occurs as a result of a compromise in the structural integrity of the aorta. If left untreated, AD can have severe consequences such as organ dysfunction or even death. Malperfusion syndrome is a major complication of aortic dissection with mesenteric malperfusion syndrome being a rare but devastating form that can lead to mesenteric ischemia and is associated with poor prognosis despite timely management. Here we report a case of a 31-year-old woman who was diagnosed with mesenteric ischemia secondary to incidental findings of aortic dissection whilst being investigated for ischemic hepatitis. She underwent emergency surgery to repair the aortic dissection but faced challenges due to unusual arterial vasculature. Despite best efforts, the patient's condition deteriorated, leading to severe brain injury. Management of aortic dissection complicated by mesenteric malperfusion remains a clinical challenge with high mortality rates and despite this, there is currently no definitive national guideline for the best management approach.

摘要

主动脉夹层(AD)是一种因主动脉结构完整性受损而引发的医疗急症。若不进行治疗,AD可能会导致诸如器官功能障碍甚至死亡等严重后果。灌注不良综合征是主动脉夹层的一种主要并发症,其中肠系膜灌注不良综合征是一种罕见但极具破坏性的形式,可导致肠系膜缺血,即便及时治疗,预后也较差。在此,我们报告一例31岁女性病例,该患者在因缺血性肝炎接受检查时,偶然发现主动脉夹层,继发肠系膜缺血。她接受了紧急手术以修复主动脉夹层,但由于异常的动脉血管结构而面临挑战。尽管尽了最大努力,患者的病情仍恶化,导致严重脑损伤。合并肠系膜灌注不良的主动脉夹层的治疗仍是一项临床挑战,死亡率很高,尽管如此,目前尚无关于最佳治疗方法的确切国家指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4a4/11662289/8ff0514315a8/cureus-0016-00000074139-i01.jpg

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