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现代尸检的价值:临床诊断与尸检诊断之间的差异

Value of autopsy in the modern age: Discrepancy between clinical and autopsy diagnoses.

作者信息

Salzillo Cecilia, Basile Roberta, Cazzato Gerardo, Ingravallo Giuseppe, Marzullo Andrea

机构信息

Department of Precision and Regenerative Medicine and Ionian Area, Pathology Unit, University of Bari "Aldo Moro", Bari 70121, Italy.

Department of Experimental Medicine, PhD Course in Public Health, University of Campania "Luigi Vanvitelli", Naples 80138, Italy.

出版信息

World J Exp Med. 2024 Dec 20;14(4):95147. doi: 10.5493/wjem.v14.i4.95147.

DOI:10.5493/wjem.v14.i4.95147
PMID:39713071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11551709/
Abstract

BACKGROUND

Autopsy is a medical procedure that consists of the examination of the corpse to determine the cause of death and obtain information on pathological conditions or injuries. In recent years, there has been a reduction in hospital autopsies and an increase in forensic autopsies.

AIM

To evaluate the utility of autopsy in the modern age and the discrepancy between clinical and autopsy diagnoses.

METHODS

A retrospective observational study was conducted on the reports of all 645 hospital autopsies performed at Polyclinic of Bari from 2006 to 2021.

RESULTS

Group A, 2006-2009, 174 cases were studied: 58% male, 58% adults, 55% neonatology; pulmonary disease was the cause of death in 23% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 55% of cases. Group B, 2010-2013, 119 cases: 52% male, 46% infants, 48% neonatology; pulmonary disease was the cause of death in 25% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 56% of cases. Group C, 2014-2017, 168 cases: sex equality, 37% infants, 25% gynecology; pulmonary disease was the cause of death in 24% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 58% of cases. Group D, 2018-2021, 184 cases: 56% male, 38% adult, 32% gynecology; pulmonary disease was the cause of death in 27% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 58% of cases.

CONCLUSION

The study of hospital autopsies reveals a 56.75% discrepancy between clinical diagnosis and autopsy, highlighting the importance of autopsies, especially for fetal and neonatal diseases, which represent 59% of cases.

摘要

背景

尸检是一种医学程序,包括对尸体进行检查以确定死因并获取有关病理状况或损伤的信息。近年来,医院尸检数量有所减少,法医尸检数量有所增加。

目的

评估现代尸检的效用以及临床诊断与尸检诊断之间的差异。

方法

对2006年至2021年在巴里综合医院进行的所有645例医院尸检报告进行回顾性观察研究。

结果

A组,2006 - 2009年,研究了174例病例:男性占58%,成年人占58%,新生儿科占55%;肺部疾病是23%病例的死因;55%的病例临床诊断与尸检诊断存在差异。B组,2010 - 2013年,119例病例:男性占52%,婴儿占46%,新生儿科占48%;肺部疾病是25%病例的死因;56%的病例临床诊断与尸检诊断存在差异。C组,2014 - 2017年,168例病例:性别平等,婴儿占37%,妇科占25%;肺部疾病是24%病例的死因;58%的病例临床诊断与尸检诊断存在差异。D组,2018 - 2021年,184例病例:男性占56%,成年人占38%,妇科占32%;肺部疾病是27%病例的死因;58%的病例临床诊断与尸检诊断存在差异。

结论

医院尸检研究显示临床诊断与尸检之间存在56.75%的差异,突出了尸检的重要性,特别是对于占病例59%的胎儿和新生儿疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c40b/11551709/efda7ef50c14/95147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c40b/11551709/efda7ef50c14/95147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c40b/11551709/efda7ef50c14/95147-g001.jpg

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Heliyon. 2023 Sep 9;9(9):e19984. doi: 10.1016/j.heliyon.2023.e19984. eCollection 2023 Sep.
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The autopsy is not dead: ongoing relevance of the autopsy.尸检未死:尸检的持续相关性
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Cause of death and the autopsy rate in an elderly population.老年人的死因和尸检率。
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The hospital autopsy: the importance in keeping autopsy an option.医院尸检:保留尸检这一选项的重要性。
Autops Case Rep. 2022 Feb 17;12:e2021333. doi: 10.4322/acr.2021.333. eCollection 2022.
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Autopsy and pre-mortem diagnostic discrepancy review in an Irish tertiary PICU.爱尔兰三级 PICU 中的尸检和生前诊断差异回顾。
Eur J Pediatr. 2021 Dec;180(12):3519-3524. doi: 10.1007/s00431-021-04155-3. Epub 2021 Jun 17.
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Risk Factors for Neonatal Mortality in Preterm Newborns in The Extreme South of Brazil.巴西极南地区早产儿新生儿死亡的危险因素。
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Assessment of an Updated Neonatal Research Network Extremely Preterm Birth Outcome Model in the Vermont Oxford Network.评估新生儿研究网络(Neonatal Research Network)更新的极早产儿结局模型在佛蒙特州牛津网络(Vermont Oxford Network)中的应用。
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