Tan Ngiap Chuan, Lim Jie En, Sultana Rehena, Quah Joanne Hui Min, Wong Wei Teen
SingHealth Polyclinics Singapore Singapore.
SingHealth Duke-NUS Family Medicine Academic Clinical Programme Singapore Singapore.
Alzheimers Dement (Amst). 2024 Dec 20;16(4):e70030. doi: 10.1002/dad2.70030. eCollection 2024 Oct-Dec.
Early detection of cognitive impairment enables interventions to slow cognitive decline. Existing neuropsychological paper-and-pencil tests may not adequately assess cognition in real-life environments. A fully-immersive and automated virtual reality (VR) system-Cognitive Assessment using VIrtual REality (CAVIRE)-was developed to assess all six cognitive domains. This case-control study aims to evaluate the ability of CAVIRE to differentiate cognitively-healthy individuals from those with cognitive impairment.
One hundred nine Asian individuals 65-84 years of age were recruited at a primary care setting in Singapore. Based on the Montreal Cognitive Assessment (MoCA), participants were grouped as either Cognitively Healthy (MoCA ≥26, = 60) or Cognitively Impaired (MoCA <26, = 49). Subsequently, all participants completed the CAVIRE assessment.
Cognitively-healthy participants achieved higher VR scores and required shorter completion time across all six cognitive domains (all 's < 0.005). Receiver-operating characteristic curve analysis showed area under the curve of 0.7267.
The results demonstrated the potential of CAVIRE as a cognitive screening tool in primary care.
CAVIRE is a virtual reality (VR) system that assesses the six cognitive domains.CAVIRE can distinguish healthy individuals from individuals with cognitive impairment.It has potential as a cognitive screening tool for older people in primary care.
认知障碍的早期检测有助于采取干预措施减缓认知衰退。现有的神经心理学纸笔测试可能无法充分评估现实生活环境中的认知能力。一种全沉浸式自动化虚拟现实（VR）系统——使用虚拟现实进行认知评估（CAVIRE）被开发出来，用于评估所有六个认知领域。本病例对照研究旨在评估CAVIRE区分认知健康个体和认知障碍个体的能力。
在新加坡的一家基层医疗诊所招募了109名65至84岁的亚洲个体。根据蒙特利尔认知评估量表（MoCA），参与者被分为认知健康组（MoCA≥26，n = 60）或认知障碍组（MoCA < 26，n = 49）。随后，所有参与者完成了CAVIRE评估。
认知健康的参与者在所有六个认知领域都获得了更高的VR分数，并且完成时间更短（所有p值<0.005）。受试者工作特征曲线分析显示曲线下面积为0.7267。
结果证明了CAVIRE作为基层医疗中认知筛查工具的潜力。
CAVIRE是一种评估六个认知领域的虚拟现实（VR）系统。CAVIRE可以区分健康个体和认知障碍个体。它有潜力作为基层医疗中老年人的认知筛查工具。
