Nguyen Van Cuong, Park Jeong Seon, Song Chang Myeon, Ji Yong Bae, Jeong Jin Hyeok, Tae Kyung
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Department of Radiology, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Head Neck. 2025 Feb;47(2):759-775. doi: 10.1002/hed.28029. Epub 2024 Dec 23.
This study aimed to evaluate the safety, efficacy, and oncologic outcomes of thermal ablation techniques, including radiofrequency, laser, and microwave ablation, in treating primary thyroid cancer compared with surgical resection.
We conducted a systematic review and network meta-analysis, which included 21 comparative studies and 40 noncomparative studies.
The three thermal ablation techniques showed significant superiority over surgical resection in terms of operative time, pain, cost, quality of life, and complications. Three years after the procedure, the tumor volume reduction and complete disappearance rates for the three thermal ablation techniques were similar, at approximately 99% and 93%-95%, respectively. The recurrence rate remained comparable (approximately 2%-3%) among the three thermal ablation techniques and surgical resection during a follow-up period exceeding 3 years.
The safety, efficacy, and oncologic outcomes of thermal ablation techniques may be acceptable and comparable to surgical resection for selected cases of primary thyroid cancer.
本研究旨在评估热消融技术（包括射频、激光和微波消融）与手术切除相比，在治疗原发性甲状腺癌方面的安全性、有效性和肿瘤学结局。
我们进行了一项系统评价和网状Meta分析，其中包括21项比较研究和40项非比较研究。
在手术时间、疼痛、成本、生活质量和并发症方面，这三种热消融技术均显示出优于手术切除的显著优势。术后三年，三种热消融技术的肿瘤体积缩小率和完全消失率相似，分别约为99%和93%-95%。在超过3年的随访期内，三种热消融技术与手术切除的复发率相当（约2%-3%）。
对于部分原发性甲状腺癌病例，热消融技术的安全性、有效性和肿瘤学结局可能是可接受的，且与手术切除相当。
