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经阴道标本取出的腹腔镜右半结肠D3淋巴结清扫术(NOSES VIIIa)治疗右半结肠癌的临床特征

Reduced-port laparoscopic right colonic resection with D3 lymph node dissection and transvaginal specimen extraction (NOSES VIIIa) for right colon cancer: clinical features.

作者信息

Efetov S K, Cao Y, Panova P D, Khlusov D I, Shulutko A M

机构信息

Department of Faculty Surgery No. 2, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

出版信息

Tech Coloproctol. 2024 Dec 23;29(1):34. doi: 10.1007/s10151-024-03055-6.

DOI:10.1007/s10151-024-03055-6
PMID:39714748
Abstract

BACKGROUND

Reduced-port laparoscopic surgery (RPLS) uses the minimum possible number of ports or small-sized ports in laparoscopic surgery. The combination of RPLS and natural orifice specimen extraction (NOSE) minimizes the procedural damage.

METHODS

A total of 17 patients diagnosed with right colon cancer were included: 5 patients in the RPLS + NOSE group and 12 patients in the conventional laparoscopic surgery (CL) + mini-laparotomy (ML) group. We highlight the key steps of the RPLS + NOSE procedure and compare the clinicopathological characteristics and short-term postoperative outcomes of the two groups.

RESULTS

Compared to CL + ML, RPLS + NOSE was associated with short hospitalization (8.80 ± 1.30 vs 13.75 ± 2.63, p = 0.001), faster first flatus (1.80 ± 0.45 vs 3.4 ± 0.90, p = 0.020) and less postoperative pain on the first day (2.40 ± 0.55 vs 4.25 ± 1.60, p = 0.025). Regarding operation time, intraoperative bleeding, tumor size, proximal and distal margin, number of lymph nodes harvested, number of positive lymph nodes, R0 resection, bowel movements, postoperative complications, Clavien-Dindo classification, Benz's classification and postoperative pain on day 1, day 3 and day 5, no significant difference was observed.

CONCLUSION

In selected patients, RPLS with D3 lymph node dissection and transvaginal specimen extraction results in fast recovery and is indicated for colon cancer patients.

摘要

背景

减孔腹腔镜手术(RPLS)在腹腔镜手术中使用尽可能少的端口或小尺寸端口。RPLS与经自然腔道标本取出术(NOSE)相结合可将手术损伤降至最低。

方法

共纳入17例诊断为右结肠癌的患者:RPLS + NOSE组5例,传统腹腔镜手术(CL)+小切口剖腹术(ML)组12例。我们重点介绍了RPLS + NOSE手术的关键步骤,并比较了两组的临床病理特征和术后短期结局。

结果

与CL + ML相比,RPLS + NOSE的住院时间较短(8.80±1.30 vs 13.75±2.63,p = 0.001),首次排气更快(1.80±0.45 vs 3.4±0.90,p = 0.020),术后第一天疼痛较轻(2.40±0.55 vs 4.25±1.60,p = 0.025)。在手术时间、术中出血、肿瘤大小、切缘近端和远端、淋巴结清扫数量、阳性淋巴结数量、R0切除、排便、术后并发症、Clavien-Dindo分类、Benz分类以及术后第1天、第3天和第5天的疼痛方面,未观察到显著差异。

结论

在选定的患者中,采用D3淋巴结清扫和经阴道标本取出的RPLS可实现快速康复,适用于结肠癌患者。

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Future Oncol. 2023 Dec;19(40):2641-2650. doi: 10.2217/fon-2023-0769. Epub 2023 Dec 18.
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Natural orifice specimen extraction surgery (NOSES) for colon cancer treatment: a double-center case-matched study of surgical and short-term postoperative outcomes.用于结肠癌治疗的经自然腔道标本取出手术(NOSES):一项关于手术及术后短期结局的双中心病例匹配研究
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Short-term and oncological outcomes of natural orifice specimen extraction surgery (NOSES) for colorectal cancer in China: a national database study of 5055 patients.
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Sci Bull (Beijing). 2022 Jul 15;67(13):1331-1334. doi: 10.1016/j.scib.2022.05.014. Epub 2022 May 19.
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Int J Surg. 2022 Aug;104:106787. doi: 10.1016/j.ijsu.2022.106787. Epub 2022 Jul 31.
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