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基于民族植物学证据筛选的摩洛哥野生可食用植物的抗菌和抗真菌活性

Antibacterial and antifungal activities of Moroccan wild edible plants selected based on ethnobotanical evidence.

作者信息

Aboukhalaf Abdelghani, Lahlou Youssef, Kalili Adil, Moujabbir Sara, Elbiyad Jamila, El Amraoui Belkassem, Belahsen Rekia

机构信息

Laboratory of Anthropogenetic, Biotechnologies and Health, Department of Biology, Faculty of Sciences, Chouaib Doukkali University, El Jadida, Morocco.

Laboratory of Control Quality in Bio-control Industry & Bioactive Molecules, Department of Biology, Faculty of Sciences, Chouaib Doukkali University, El Jadida, Morocco.

出版信息

Rocz Panstw Zakl Hig. 2024 Dec 23;75(3):229-236. doi: 10.32394/rpzh/192206. Epub 2024 Sep 10.

Abstract

BACKGROUND

Despite the extensive literature focusing on identifying novel antimicrobials of plant origin, little work has been undertaken to examine the antimicrobial activity of wild edible plants.

OBJECTIVE

The current research aimed to determine the in vitro antimicrobial activity of methanolic extract of some common wild edible plants.

MATERIAL AND METHODS

Disc diffusion and broth micro dilution methods were used to evaluate the antimicrobial activity of extracts of , , , , , , and against known human microorganisms' pathogens.

RESULTS

The result indicated that most of the extracts exhibited a range of growth inhibitory action against all bacterial strains and yeasts tested with inhibition zones ranging from 11 mm to 32 mm, MIC value ranging from 0.048 to 50 mg/ml and MBC and MFC values ranging from 0.048 to 100 mg/ml. Among the seven plant extracts tested, was the most effective showing high antimicrobial activity against all tested microbial strains. All plant extracts exhibited bactericidal activities against all the tested bacteria strains except for those of , and which showed a bacteriostatic activity against and sp. Antifungal activity was shown only by, and against both and .

CONCLUSIONS

These findings highlight the potential of wild edible plants to control human pathogenic microbes and demonstrate that these plants could be used as starting points for the development of novel antimicrobial compounds.

摘要

背景

尽管有大量文献聚焦于鉴定植物源新型抗菌剂,但对野生可食用植物抗菌活性的研究却很少。

目的

当前研究旨在测定一些常见野生可食用植物甲醇提取物的体外抗菌活性。

材料与方法

采用纸片扩散法和肉汤微量稀释法评估 、 、 、 、 、 和 的提取物对已知人类微生物病原体的抗菌活性。

结果

结果表明,大多数提取物对所有测试的细菌菌株和酵母均表现出一定范围的生长抑制作用,抑菌圈范围为11毫米至32毫米,最低抑菌浓度(MIC)值为0.048至50毫克/毫升,最低杀菌浓度(MBC)和最低杀真菌浓度(MFC)值为0.048至100毫克/毫升。在所测试的七种植物提取物中, 最有效,对所有测试的微生物菌株均表现出高抗菌活性。除了 、 和 对 及 表现出抑菌活性外,所有植物提取物对所有测试的细菌菌株均表现出杀菌活性。仅 、 和 对 和 表现出抗真菌活性。

结论

这些发现突出了野生可食用植物在控制人类致病微生物方面的潜力,并表明这些植物可作为开发新型抗菌化合物的起点。

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