一种用于量化月经周期中可穿戴设备获取的每日心血管参数波动的新方法。

A Novel method for quantifying fluctuations in wearable derived daily cardiovascular parameters across the menstrual cycle.

作者信息

Jasinski Summer R, Presby David M, Grosicki Gregory J, Capodilupo Emily R, Lee Victoria H

机构信息

Whoop Inc., Data Science and Research, Boston, MA, USA.

Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.

出版信息

NPJ Digit Med. 2024 Dec 23;7(1):373. doi: 10.1038/s41746-024-01394-0.

Currently, knowledge of changes in cardiovascular function across the menstrual cycle and how these changes may inform upon underlying health is limited. Utilizing wrist-worn biometric data we developed a novel measure to quantify and investigate the cardiovascular fluctuation (i.e. cardiovascular amplitude) within resting heart rate (RHR) and heart rate variability (RMSSD) across 11,590 participants and 45,811 menstrual cycles. Within participants, RHR and RMSSD fluctuated in a regular pattern throughout the menstrual cycle, with population RHR and RMSSD at cycle day 5, RHR at day 26, and RMSSD at day 27. Cardiovascular amplitude was attenuated (p < 0.05) in older participants and participants using birth control, suggesting the novel metric may mirror differences in hormonal fluctuations in these cohorts. Longitudinal tracking of cardiovascular amplitude may offer accessible non-invasive monitoring of female physiology and underlying health across the menstrual cycle.

目前，关于月经周期中心血管功能的变化以及这些变化如何反映潜在健康状况的知识有限。我们利用佩戴在手腕上的生物特征数据，开发了一种新方法，对11590名参与者的45811个月经周期内静息心率（RHR）和心率变异性（RMSSD）中的心血管波动（即心血管幅度）进行量化和研究。在参与者中，RHR和RMSSD在整个月经周期中呈规律波动，群体RHR和RMSSD在周期第5天、RHR在第26天、RMSSD在第27天出现变化。老年参与者和使用避孕药的参与者的心血管幅度减弱（p<0.05），这表明这种新指标可能反映了这些队列中激素波动的差异。对心血管幅度进行纵向跟踪，可能为整个月经周期的女性生理和潜在健康状况提供便捷的非侵入性监测。