Zhang Zhiyi, Yan Jiayu, Yan Jun, Huang Liuming, Chen Yajun, Ni Xin
Department of General Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Department of Emergency Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Pediatr Surg Int. 2024 Dec 23;41(1):44. doi: 10.1007/s00383-024-05955-y.
To investigate the clinical characteristics and surgical management of children with Burkitt's lymphoma (BL) involving the gastrointestinal tract.
A retrospective analysis was conducted on 87 pediatric patients diagnosed with BL involving the gastrointestinal tract and treated surgically at Beijing Children's Hospital (2008-2022). All patients were histopathologically confirmed with BL and diagnosed with gastrointestinal involvement through imaging studies and surgery. Clinical data were reviewed and analyzed.
Among 87 patients, 79 were male and 8 were female, with an average age of 6.8 ± 3.3 years. Predominant clinical manifestations included abdominal pain (74/87, 85.1%) and abdominal mass (45/87, 51.7%). The ileocecal region (31/87, 35.6%) was the most frequent involvement site. The presence of intussusception (58/87, 66.7%) was the main indication for surgery, of which 56 (56/58, 96.6%) underwent enterectomy and anastomosis. Twenty-two (22/87, 25.3%) patients underwent surgery for abdominal mass, with 15 (15/22, 68.2%) receiving an open biopsy. During the follow-up period, 2 patients (2/83, 2.4%) experienced recurrence, 4 patients (4/83, 4.8%) required reoperation, and no deaths were reported.
The main surgical indications for gastrointestinal BL are intussusception and abdominal mass. Surgery plays a crucial role in resolving intussusception, clarifying the diagnosis, and ultimately facilitating the timely initiation of chemotherapy without delay.
探讨伯基特淋巴瘤（BL）累及胃肠道患儿的临床特征及手术治疗方法。
对2008年至2022年在北京儿童医院接受手术治疗的87例诊断为BL累及胃肠道的儿科患者进行回顾性分析。所有患者均经组织病理学确诊为BL，并通过影像学检查和手术诊断为胃肠道受累。对临床资料进行回顾性分析。
87例患者中，男性79例，女性8例，平均年龄6.8±3.3岁。主要临床表现为腹痛（74/87，85.1%）和腹部肿块（45/87，51.7%）。回盲部（31/87，35.6%）是最常受累部位。肠套叠（58/87，66.7%）是手术的主要指征，其中56例（56/58，96.6%）行肠切除吻合术。22例（22/87，25.3%）患者因腹部肿块接受手术，15例（15/22，68.2%）接受了开放活检。随访期间，2例患者（2/83，2.4%）复发，4例患者（4/83，4.8%）需要再次手术，无死亡病例报告。
胃肠道BL的主要手术指征是肠套叠和腹部肿块。手术在解决肠套叠、明确诊断以及最终促进及时开始化疗方面起着关键作用。
