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中国高龄成年人中黑碳空气污染与死亡事件:一项前瞻性队列研究

Black Carbon Air Pollution and Incident Mortality Among the Advance-Aged Adults in China: A Prospective Cohort Study.

作者信息

Zhu Anna, Kan Haidong, Shi Xiaoming, Zeng Yi, Ji John S

机构信息

Vanke School of Public Health, Tsinghua University, Beijing, China.

School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai, China.

出版信息

J Gerontol A Biol Sci Med Sci. 2025 Mar 7;80(4). doi: 10.1093/gerona/glae302.

Abstract

BACKGROUND

We aimed to assess associations between black carbon (BC) and nonaccidental mortality among advance-aged adults in China.

METHODS

We conducted a prospective cohort study in 22 provinces of Chinese Longitudinal Healthy Longevity Survey. We calculated concentrations of 3-year average BC, fine particulate matter (PM2.5), and other PM2.5 components (SO42-, NO3-, NH4+, and organic matter) at individual levels. We used Cox proportional hazards models to assess dose-response BC exposure on nonaccidental mortality, adjusted for total PM2.5, green space, temperature, humidity, and demographic covariates.

RESULTS

We studied 12 873 participants, with a median age of 88 years and 57.4% females. For a median follow-up of 4 years, we observed 7 426 mortality events. The mean 3-year average BC and total PM2.5 exposure concentrations were 3.49 and 66.97 μg/m3, respectively. An increase of 1 μg/m3 in BC was associated with a 39% increase in mortality risks (HR: 1.39, 95% CI: 1.36, 1.43), notably higher than the corresponding increase in mortality risks linked to total PM2.5 (HR: 1.003, 95% CI: 1.002, 1.004) in the adjusted model. The stratified analyses show that people living in rural areas, with lower social and leisure activity index, and lower physical activity, were at greater risk from BC exposure.

CONCLUSIONS

BC is a strong predictor of mortality, with a higher effect estimate compared with total PM2.5 and other PM2.5 components, particularly in rural populations. Although total PM2.5 has been a target indicator of clean air policy interventions, our results indicate that BC concentration should be routinely measured, reported, and studied to improve public health.

摘要

背景

我们旨在评估中国老年人群中黑碳(BC)与非意外死亡率之间的关联。

方法

我们在中国健康与养老追踪调查的22个省份开展了一项前瞻性队列研究。我们计算了个体水平上3年平均BC、细颗粒物(PM2.5)及其他PM2.5成分(SO42-、NO3-、NH4+和有机物)的浓度。我们使用Cox比例风险模型评估BC暴露剂量与非意外死亡率之间的剂量反应关系,并对总PM2.5、绿地、温度、湿度和人口统计学协变量进行了校正。

结果

我们研究了12873名参与者,中位年龄为88岁,女性占57.4%。中位随访4年期间,我们观察到7426例死亡事件。3年平均BC和总PM2.5暴露浓度分别为3.49和66.97μg/m3。BC每增加1μg/m3,死亡风险增加39%(风险比:1.39,95%置信区间:1.36,1.43),在调整模型中显著高于与总PM2.5相关的死亡风险相应增加幅度(风险比:1.003,95%置信区间:1.002,1.004)。分层分析表明,生活在农村地区、社会和休闲活动指数较低以及身体活动较少的人群,BC暴露风险更高。

结论

BC是死亡率的有力预测指标,与总PM2.5及其他PM2.5成分相比,其效应估计更高,尤其是在农村人群中。尽管总PM2.5一直是清洁空气政策干预的目标指标,但我们的结果表明,应常规测量、报告和研究BC浓度,以改善公众健康。

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