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零切迹椎间融合联合钛网钢板治疗多节段脊髓型颈椎病

[Zero-profile intervertebral fusion with cage-titanium plate for the treatment of multilevel cervical spondylotic myelopathy].

作者信息

Zhong Jian-Bin, Hu Yong, Chu Zhen-Tao, Dong Wei-Xin, Yuan Zhen-Shan, Sun Xiao-Yang, Zhu Bing-Ke, Lai Ou-Jie

机构信息

Department of Spine Surgery, Ningbo No.6 Hospital, Ningbo 315040, Zhejiang, China.

Medical School of Ningbo University, Ningbo 315211, Zhejiang, China.

出版信息

Zhongguo Gu Shang. 2024 Dec 25;37(12):1188-95. doi: 10.12200/j.issn.1003-0034.20230328.

Abstract

OBJECTIVE

To explore clinical effect of Zero-profile intervertebral fusion with cage-titanium plate in treating multilevel cervical spondylotic myelopathy.

METHODS

From January 2016 to January 2020, 107 patients with multisegmental cervical spondylotic myelopathy treated by surgery were retrospectively analyzed and divided into Hybrid group and control group according to different surgical methods. There were 54 patients in Hybrid group, including 42 males and 12 females, aged from 33 to 77 years old with an average of (57.3±9.5) years old;20 patients with C-C, 27 patients with C-C and 7 patients with C-C;Zero-profile intervertebral fusion with cage-titanium plate internal fixation was performed. There were 53 patients in control group, including 34 males and 19 females;aged from 36 to 79 years old with an average of (57.8±8.9) years old;17 patients with C-C, 27 patients with C-C, and 9 patients with C-C;titanium plate interbody fusion fixation was performed. Operation time, blood loss and complications between two groups were compared, visual analogue scale (VAS), Japanese Orthopedic Association (JOA) scores and neck disability index (NDI) were used to assess recovery of clinical symptoms;cervical lordosis (CL), cervical sagittal vertical axis (C-SVA), and T slope (TS) were measured and compared to evaluate cervical sagittal plane parameters.

RESULTS

All patients were followed up, Hybrid group was followed up for 24 to 64 months with an average of (31.7±18.4) months, and control group was followed up for 24 to 65 months with an average of (32.6±15.8) months. There was no significant difference in follow-up time between two groups (>0.05). Operation time and blood loss in Hybrid group were less than those in control group (<0.05). VAS, JOA score and NDI were significantly improved between two groups at the lastest follow-up (<0.05). There were no significant difference in VAS, JOA and NDI scores between two groups before and after operation (>0.05). CL in both two groups at 3 months and the latest follow-up after operation were significantly improved than those before operation (<0.05), there were no significant difference between two groups in T1S and C-SVA before and after operation (>0.05). Postoperative dysphagia occurred in 2 patients in Hybrid group and 9 patients in control group, and had statistically difference in the incidence of dysphagia between two groups (=5.112, =0.024). During the follow-up, there were no complications such as loosening, displacement or fracture of internal fixation between two groups.

CONCLUSION

Compared with titanium plate interbody fusion, Zero-profile intervertebral fusion combined with cage-titanium plate for the treatment of multilevel cervical spondylotic myelopathy could shorten surgical time and blood loss, reduce surgical trauma and postoperative swallowing difficulties, and is conducive to early and rapid recovery.

摘要

目的

探讨零切迹椎间融合钛网钢板治疗多节段脊髓型颈椎病的临床疗效。

方法

回顾性分析2016年1月至2020年1月手术治疗的107例多节段脊髓型颈椎病患者,根据不同手术方式分为混合组和对照组。混合组54例,男42例,女12例,年龄33~77岁,平均(57.3±9.5)岁;C3~C4 20例,C4~C5 27例,C5~C6 7例;行零切迹椎间融合钛网钢板内固定。对照组53例,男34例,女19例;年龄36~79岁,平均(57.8±8.9)岁;C3~C4 17例,C4~C5 27例,C5~C6 9例;行钛板椎体间融合固定。比较两组手术时间、出血量及并发症情况,采用视觉模拟评分法(VAS)、日本骨科协会(JOA)评分及颈部功能障碍指数(NDI)评估临床症状恢复情况;测量并比较颈椎前凸(CL)、颈椎矢状垂直轴(C-SVA)及T1斜率(T1S)以评估颈椎矢状面参数。

结果

所有患者均获随访,混合组随访24~64个月,平均(31.7±18.4)个月,对照组随访24~65个月,平均(32.6±15.8)个月。两组随访时间差异无统计学意义(P>0.05)。混合组手术时间及出血量少于对照组(P<0.05)。末次随访时两组VAS、JOA评分及NDI均较术前显著改善(P<0.05)。两组术前、术后VAS、JOA及NDI评分差异无统计学意义(P>0.05)。两组术后3个月及末次随访时CL均较术前显著改善(P<0.05),两组术前、术后T1S及C-SVA差异无统计学意义(P>0.05)。混合组术后吞咽困难2例,对照组9例,两组吞咽困难发生率差异有统计学意义(χ²=5.112,P=0.024)。随访期间两组均未出现内固定松动、移位或断裂等并发症。

结论

与钛板椎体间融合相比,零切迹椎间融合钛网钢板治疗多节段脊髓型颈椎病可缩短手术时间及减少出血量,降低手术创伤及术后吞咽困难的发生,有利于早期快速恢复。

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