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通过皮质-皮质经颅磁刺激推进工作记忆研究。

Advancing working memory research through cortico-cortical transcranial magnetic stimulation.

作者信息

Phylactou Phivos, Konstantinou Nikos, Ester Edward F

机构信息

Faculty of Health Sciences, School of Physical Therapy, University of Western Ontario, London, ON, Canada.

The Gray Centre for Mobility and Activity, Parkwood Institute, London, ON, Canada.

出版信息

Front Hum Neurosci. 2024 Dec 9;18:1504783. doi: 10.3389/fnhum.2024.1504783. eCollection 2024.

Abstract

The neural underpinnings of working memory (WM) have been of continuous scientific interest for decades. As the understanding of WM progresses and new theories, such as the distributed view of WM, develop, the need to advance the methods used to study WM also arises. This perspective discusses how building from the state-of-the-art in the field of transcranial magnetic stimulation (TMS), and utilising cortico-cortical TMS, may pave the way for testing some of the predictions proposed by the distributed WM view. Further, after briefly discussing current barriers that need to be overcome for implementing cortico-cortical TMS for WM research, examples of how cortico-cortical TMS may be employed in the context of WM research are provided, guided by the ongoing debate on the sensory recruitment framework.

摘要

几十年来,工作记忆(WM)的神经基础一直是科学界持续关注的焦点。随着对工作记忆理解的不断深入以及诸如工作记忆分布式观点等新理论的发展,改进用于研究工作记忆的方法的需求也随之出现。本文探讨了如何在经颅磁刺激(TMS)领域现有技术水平的基础上,利用皮质 - 皮质TMS为检验分布式工作记忆观点提出的一些预测开辟道路。此外,在简要讨论了将皮质 - 皮质TMS应用于工作记忆研究需要克服的当前障碍之后,结合关于感觉募集框架的持续争论,给出了皮质 - 皮质TMS在工作记忆研究背景下可能的应用示例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c99/11663928/1888234149ef/fnhum-18-1504783-g001.jpg

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