The Impact of Deep Local Lung Hyperthermia on COVID-19 Cancer Patients.

BACKGROUND

The goal of this study was to assess the impact of deep local hyperthermia on oxygen (O) saturation and infected volumes of lungs on coronavirus disease 2019 (COVID-19) cancer patients.

MATERIALS AND METHODS

Fifty patients who suffered from COVID-19 (according to their computed tomography (CT) images and laboratory findings) were included in this study. The mentioned patients were divided into two groups (I and II) with thirty-five participants. The infected volumes and COVID-19 infectious locations were diagnosed using their CT images, and deep local hyperthermia was performed for group II. After three consequent days, the SPO D-dimer, and infected volumes of lung parenchyma of both groups were compared to each other.

RESULTS

For group II, the mean ± SD (standard deviation) of O pressure saturation (SPO) before/after hyperthermia was 85 ± 0.0/91.3 ± 0.5, respectively, while for group I, the mean ± SD of SPO before/after 3 days was 85 ± 0.0/88 ± 0.2, respectively. For infected volumes of lungs before/after hyperthermia in group II, the mean ± SD was 31.36 ± 3.13/4 ± 1.53, respectively. Nonetheless, the infected volumes of lungs for group I were 34.21 ± 3.41/10 ± 2.12 before/after three days. For group II, the amount of D-dimer before/after hyperthermia was 3200 ± 106/510 ± 121, respectively. However, for group I, it was 3100/740 before/after the consequent three days, respectively.

CONCLUSION

Deep local lung hyperthermia for COVID-19 cancer patients is suggested, as a result of its positive impacts on SPO improvement and also D-dimer serum level, C-reactive protein, and Lactate dehydrogenaze reduction for the mentioned patients.