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伤寒沙门菌感染的一种罕见且危及生命的并发症:来自印度的病例报告,凸显沙门菌败血症的诊断和治疗挑战

A Rare and Life-Threatening Complication of Salmonella Typhi Infection: A Case Report From India Highlighting Diagnostic and Therapeutic Challenges in Salmonella Sepsis.

作者信息

Jabeen Jaziya, Ardra M, Valsan Chithra, Paul John, Paul Cherish

机构信息

Cardiology, Royal Cornwall Hospital, Cornwall, GBR.

Microbiology, Jubilee Mission Medical College & Research Institute, Thrissur, IND.

出版信息

Cureus. 2024 Dec 23;16(12):e76234. doi: 10.7759/cureus.76234. eCollection 2024 Dec.

Abstract

Salmonella infections are widely known to cause gastroenteritis, especially in areas of poor hygiene and sanitation. Common symptoms include sustained fever, chills, and abdominal pain. Sepsis, disseminated intravascular coagulation (DIC), various neurological manifestations, and multiorgan failure are other uncommon presentations. Raising appropriate awareness about its clinical spectrum is therefore crucial, even in the absence of typical symptoms. The following case of a 34-year-old Indian female who developed -induced sepsis addresses various challenges involved in diagnosing and treating the condition. The case was successfully managed with rapid diagnostics, targeted antibiotic therapy, and supportive care. Recognizing the condition early and providing necessary treatment is therefore vital to preventing substantial morbidity and mortality. To improve outcomes for critically ill patients, it is important that the causative organism be identified quickly and appropriate treatment be commenced. Here, we present a case of Salmonella sepsis complicated by DIC, its clinical course, and the diagnostic and treatment modalities we have followed.

摘要

沙门氏菌感染广为人知会引发肠胃炎,尤其是在卫生和环境卫生较差的地区。常见症状包括持续发热、寒战和腹痛。败血症、弥散性血管内凝血(DIC)、各种神经表现以及多器官衰竭是其他不常见的表现。因此,即使没有典型症状,提高对其临床谱的适当认识也至关重要。以下是一名34岁印度女性发生[具体诱因未提及]诱发败血症的病例,该病例涉及诊断和治疗该病症的各种挑战。该病例通过快速诊断、靶向抗生素治疗和支持性护理成功得到管理。因此,早期识别病情并提供必要治疗对于预防严重的发病率和死亡率至关重要。为改善重症患者的预后,快速识别致病微生物并开始适当治疗非常重要。在此,我们呈现一例并发弥散性血管内凝血的沙门氏菌败血症病例、其临床病程以及我们所采用的诊断和治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d361/11665481/3723fda8f324/cureus-0016-00000076234-i01.jpg

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