Sun Cuilian, Na Yuhang, Wang Ziyu, Zhu Tingting, Liu Xiaojuan
Department of Pathogen Biology, Medical College, Nantong University, Nantong, Jiangsu, China.
Medical College, Nantong University, Nantong, Jiangsu, China.
Front Pharmacol. 2024 Dec 9;15:1476670. doi: 10.3389/fphar.2024.1476670. eCollection 2024.
The excessive proliferation of is an important reason for the occurrence of acne vulgaris, and genetic detection ratio of in acne is as high as 60.5%. Until now, the treatment of is mainly limited to antibiotics, but some strains of produce antimicrobial resistances, making it difficult for clinical treatment. Additionally, antibiotics can cause severe adverse effects. Therefore, more and more people are paying attention to phytochemicals. It is well known that plants can synthesize a range of secondary metabolites, named phytochemicals, part of which have antibacterial properties. Additionally, the main advantages of phytochemicals are that they have good efficacies and less side effects, so they are suitable choices for medical treatment. This review mainly discusses the effects and mechanisms of phytochemicals against .
[此处原文中第一个“is”前缺少具体内容,第二个“is”前也缺少具体内容,无法准确翻译。推测完整句子可能是The excessive proliferation of Propionibacterium acnes is an important reason for the occurrence of acne vulgaris, and genetic detection ratio of Propionibacterium acnes in acne is as high as 60.5%. 以下是基于推测的完整译文]
痤疮丙酸杆菌的过度增殖是寻常痤疮发生的一个重要原因,痤疮中痤疮丙酸杆菌的基因检测率高达60.5%。到目前为止,痤疮丙酸杆菌的治疗主要局限于抗生素,但某些痤疮丙酸杆菌菌株会产生抗菌耐药性,给临床治疗带来困难。此外,抗生素会引起严重的不良反应。因此,越来越多的人开始关注植物化学物质。众所周知,植物可以合成一系列次生代谢产物,称为植物化学物质,其中一部分具有抗菌特性。此外,植物化学物质的主要优点是疗效好且副作用小,因此它们是医疗治疗的合适选择。这篇综述主要讨论了植物化学物质对痤疮丙酸杆菌的作用和机制。