Wang Yuan, Zhang Jiajia, Wang Shan, Wu Yibo, Hang Ling, Hua Yuming, Shi Weifeng
Human Reproductive and Genetic Center, Affiliated Hospital of Jiangnan University, Wuxi, China.
Wuxi Furen Senior High School, Wuxi, China.
Asia Pac J Oncol Nurs. 2024 Nov 14;12:100621. doi: 10.1016/j.apjon.2024.100621. eCollection 2025 Dec.
This study aimed to assess the feasibility, acceptability, and preliminary efficacy of a Systematic Transaction Model (STM)-guided dyadic coping nursing intervention for patients with breast cancer and their spouses.
A single-arm, pre-test/post-test pilot study was conducted at a tertiary hospital in Wuxi, China, recruiting 28 breast cancer patient-caregiver pairs. Each dyad participated in six hybrid intervention sessions. Paired t-tests were used to evaluate pre- and post-intervention changes, and effect sizes were calculated. Feasibility was assessed by recruitment and retention rates, acceptability via the Client Satisfaction Questionnaire-8 (CSQ-8), and preliminary efficacy through measures of body image, dyadic coping, post-traumatic growth, and marital satisfaction.
All 28 dyads completed the intervention. Patients showed small-to-moderate improvements in body image, post-traumatic growth, dyadic coping, and marital satisfaction ( = 0.4-0.5, ≤ 0.022), with clinically meaningful changes observed in 39%-68% of patients. Spousal caregivers also demonstrated improvements in post-traumatic growth, dyadic coping, and marital satisfaction ( = 0.3-0.6, ≤ 0.033), with 36%-46% showing clinically important differences.
This pilot study supports the feasibility and initial efficacy of an STM-guided dyadic coping intervention, which may benefit breast cancer patients and their spouses as a unit. Further large-scale trials are recommended to validate these findings.
China Clinical Trial Registry (ChiCTR2400083416).
本研究旨在评估系统交易模型（STM）指导的二元应对护理干预对乳腺癌患者及其配偶的可行性、可接受性和初步疗效。
在中国无锡的一家三级医院进行了一项单臂、干预前/干预后试点研究，招募了28对乳腺癌患者-照顾者。每对参与者参加了六次混合干预课程。采用配对t检验评估干预前后的变化，并计算效应量。通过招募和保留率评估可行性，通过客户满意度问卷-8（CSQ-8）评估可接受性，并通过身体形象、二元应对、创伤后成长和婚姻满意度的测量评估初步疗效。
所有28对均完成了干预。患者在身体形象、创伤后成长、二元应对和婚姻满意度方面有小到中等程度的改善（=0.4-0.5，≤0.022），39%-68%的患者观察到具有临床意义的变化。配偶照顾者在创伤后成长、二元应对和婚姻满意度方面也有改善（=0.3-0.6，≤0.033），36%-46%的人显示出具有临床重要意义的差异。
这项试点研究支持了STM指导的二元应对干预的可行性和初步疗效，该干预可能使乳腺癌患者及其配偶作为一个整体受益。建议进一步进行大规模试验以验证这些发现。
中国临床试验注册中心（ChiCTR2400083416）。
