Bethke B A, Schubert G E
Dtsch Med Wochenschr. 1985 Mar 1;110(9):343-6. doi: 10.1055/s-2008-1068825.
In a prospective study conducted during one year, postmortem examination of 500 unselected adults revealed in 13 cases (2.6%) a marked capillarosclerosis of the mucosa of the renal pelvis, considered to be a reliable histological sign of phenacetin and paracetamol abuse. These results were obtained in four men (1.5% of the total number of autopsied men) and nine women (3.9% of the autopsied women). Thus, capillarosclerosis is 2.6 time more frequent in women than in men.
在一项为期一年的前瞻性研究中,对500名未经挑选的成年人进行尸检后发现,13例(2.6%)患者存在肾盂黏膜明显的毛细血管硬化,这被认为是滥用非那西丁和对乙酰氨基酚的可靠组织学征象。这些结果在4名男性(占尸检男性总数的1.5%)和9名女性(占尸检女性总数的3.9%)中获得。因此,毛细血管硬化在女性中的发生率是男性的2.6倍。