经后外侧入路经皮内镜下腰椎间盘切除术的隐性失血
Hidden blood loss in percutaneous endoscopic lumbar discectomy via the posterolateral approach.
作者信息
Liu Jin-Wang, Li Shao-Xing, Wang Fei, Yang Yun, Yu Hua
机构信息
Department of Orthopaedics, The Third People's Hospital of Chengdu, Sichuan, PR China.
出版信息
Jt Dis Relat Surg. 2025 Jan 2;36(1):56-64. doi: 10.52312/jdrs.2025.2065. Epub 2024 Dec 18.
OBJECTIVES
The study aimed to evaluate the hidden blood loss (HBL) and its possible risk factors in patients with lumbar disc herniation undergoing percutaneous endoscopic lumbar discectomy (PELD) via posterolateral approach.
PATIENTS AND METHODS
The clinical data of 170 lumbar disc herniation patients (101 males, 69 females; mean age: 57.7±18.0 years; range, 19 to 87 years) treated with PELD via posterolateral approach between January 2021 and January 2023 were retrospectively analyzed. Demographic characteristics, laboratory data, and surgery-related clinical data of the patients were collected, including age, sex, height, weight, body mass index, albumin, blood glucose, hemoglobin (Hb), hematocrit (Hct), American Society of Anesthesiologists (ASA) score, surgical time, number of puncture, and the need for foramenoplasty. Hidden blood loss was calculated, and multiple linear regression analysis was performed to identify risk factors.
RESULTS
The mean Hb in patients with preoperative anemia was 115.8±8.6 g/L. The mean postoperative Hb loss and Hct loss were 7.0±4.5 g/L and 0.02±0.01%, respectively. The mean number of punctures (1-3 punctures vs. >3 punctures) was 2.4±0.7 and 4.6±0.6, respectively. Satisfactory localization was achieved within three punctures in nearly 60% of the patients. More than half (55.3%) of the patients underwent foraminoplasty. The mean surgical time was 110.9±32.0 min. The mean HBL was 178.4±66.5 mL. The mean follow-up time was 6.9±2.2 months. When comparing the preoperative and postoperative incidence of anemia, we found that the incidence of anemia was significantly associated with HBL (p<0.001). Multiple linear regression analysis showed that HBL was positively correlated with the number of punctures, foraminoplasty, and surgical time.
CONCLUSION
Our results suggest that the number of punctures, foraminoplasty, and surgical time are independent risk factors for HBL after PELD via posterolateral approach. Therefore, HBL should not be ignored in patients with these risk factors to ensure patients' safety in the perioperative period.
目的
本研究旨在评估经后外侧入路行经皮内镜下腰椎间盘切除术(PELD)的腰椎间盘突出症患者的隐性失血(HBL)及其可能的危险因素。
患者与方法
回顾性分析2021年1月至2023年1月间采用后外侧入路PELD治疗的170例腰椎间盘突出症患者(男101例,女69例;平均年龄:57.7±18.0岁;范围19至87岁)的临床资料。收集患者的人口统计学特征、实验室数据及手术相关临床资料,包括年龄、性别、身高、体重、体重指数、白蛋白、血糖、血红蛋白(Hb)、血细胞比容(Hct)、美国麻醉医师协会(ASA)评分、手术时间、穿刺次数及是否需要进行椎间孔成形术。计算隐性失血量,并进行多元线性回归分析以确定危险因素。
结果
术前贫血患者的平均Hb为115.8±8.6 g/L。术后平均Hb丢失量和Hct丢失量分别为7.0±4.5 g/L和0.02±0.01%。平均穿刺次数(1 - 3次穿刺与>3次穿刺)分别为2.4±0.7次和4.6±0.6次。近60%的患者在3次穿刺内实现满意定位。超过一半(55.3%)的患者进行了椎间孔成形术。平均手术时间为110.9±32.0分钟。平均HBL为178.4±66.5 mL。平均随访时间为6.9±2.2个月。比较术前和术后贫血发生率时,我们发现贫血发生率与HBL显著相关(p<0.001)。多元线性回归分析显示,HBL与穿刺次数、椎间孔成形术及手术时间呈正相关。
结论
我们的结果表明,穿刺次数、椎间孔成形术及手术时间是后外侧入路PELD术后HBL的独立危险因素。因此,对于存在这些危险因素的患者,不应忽视HBL,以确保患者围手术期的安全。