Xiao Long, Zhou Jianhong, Zhong Qin, Zhang Xiaobo, Cao Xuefei
Department of Orthopedics, the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, 550000, PR China.
Clinical Medical Research Center, Affiliated Hospital of Guizhou Medical University, No.28 Beijing Road, Guiyang City, 550001, Guizhou Province, China.
Sci Rep. 2025 May 2;15(1):15347. doi: 10.1038/s41598-025-99959-w.
This study investigated the comparative effectiveness of unilateral biportal endoscopic discectomy (UBED) and percutaneous endoscopic lumbar discectomy (PELD) in managing lumbar disc herniation (LDH). Clinical data from 146 LDH patients treated surgically at the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine (January 2020-January 2023) were retrospectively analyzed. Patients were categorized into UBED (n = 84) and PELD (n = 62) groups. Key metrics such as surgical time, incision length, fluoroscopy frequency, blood loss, hospital stay, complications, visual analog scale (VAS) scores, and the Oswestry Disability Index (ODI) were compared. The average age of patients in the UBED group was 53.46 ± 15.60 years, whereas the average age of patients in the PELD group was 55.61 ± 15.52 years (P = 0.411). Their BMI was 24.17 ± 2.94 and 23.90 ± 2.61, respectively (P = 0.558). The duration of symptoms was 10.52 ± 5.23 months in the UBED group and 11.66 ± 6.02 months in the PELD group (P = 0.225). The surgical time was 66.67 ± 15.83 min in the UBED group and 69.11 ± 25.84 min in the PELD group (P = 0.481). Intraoperative blood loss was 76.81 ± 26.74 ml in the UBED group and 69.44 ± 25.74 ml in the PELD group (P = 0.096). The hospital stay was 5.39 ± 1.83 days in the UBED group and 5.11 ± 3.42 days in the PELD group (P = 0.525). The average follow-up time was 16.46 ± 4.52 months in the UBED group and 15.71 ± 3.83 months in the PELD group (P = 0.289). Compared with those before the operation, the VAS score, JOA score, and ODI of both groups significantly improved on the first day postoperatively, at 3 months, and at 6 months. No significant intergroup differences were noted in terms of intraoperative blood loss, hospital stay, or postoperative functional scores. Both groups showed marked postoperative improvements in functional outcomes. The postoperative satisfaction rates of patients in the UBED group and PELD group were 91.7% and 87.1%, respectively. Notably, the UBED group demonstrated a reduced fluoroscopy frequency and significantly lower rates of complications and recurrence. In terms of imaging, the disc Height of the two groups of patients showed a slight decrease after surgery, whereas the spinal canal area increased compared to before surgery, and there was no difference between the groups. UBED and PELD effectively alleviate LDH symptoms, but UBED has advantages in reducing fluoroscopy dependence, complications, and recurrence.
本研究调查了单侧双孔通道内镜下椎间盘切除术(UBED)与经皮内镜下腰椎间盘切除术(PELD)治疗腰椎间盘突出症(LDH)的相对疗效。回顾性分析了2020年1月至2023年1月在贵州中医药大学第一附属医院接受手术治疗的146例LDH患者的临床资料。将患者分为UBED组(n = 84)和PELD组(n = 62)。比较了手术时间、切口长度、透视次数、失血量、住院时间、并发症、视觉模拟评分(VAS)、日本骨科学会(JOA)评分和Oswestry功能障碍指数(ODI)等关键指标。UBED组患者的平均年龄为53.46±15.60岁,而PELD组患者的平均年龄为55.61±15.52岁(P = 0.411)。他们的体重指数分别为24.17±2.94和23.90±2.61(P = 0.558)。UBED组症状持续时间为10.52±5.23个月,PELD组为11.66±6.02个月(P = 0.225)。UBED组手术时间为66.67±15.83分钟,PELD组为69.11±25.84分钟(P = 0.481)。UBED组术中失血量为76.81±26.74毫升,PELD组为69.44±25.74毫升(P = 0.096)。UBED组住院时间为5.39±1.83天,PELD组为5.11±3.42天(P = 0.525)。UBED组平均随访时间为16.46±4.52个月,PELD组为15.71±3.83个月(P = 0.289)。与术前相比,两组患者术后第1天、3个月和6个月的VAS评分及JOA评分、ODI均显著改善。两组在术中失血量、住院时间或术后功能评分方面无显著组间差异。两组术后功能结局均有明显改善。UBED组和PELD组患者术后满意度分别为91.7%和87.1%。值得注意的是,UBED组的透视次数减少,并发症和复发率显著降低。影像学方面,两组患者术后椎间盘高度略有下降,而椎管面积较术前增加,组间无差异。UBED和PELD均能有效缓解LDH症状,但UBED在减少对透视的依赖、并发症和复发方面具有优势。