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2
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Ann Vasc Surg. 2020 May;65:82-89. doi: 10.1016/j.avsg.2019.10.082. Epub 2019 Nov 1.
3
Completion of the Updated Caprini Risk Assessment Model (2013 Version).更新后的卡普兰风险评估模型(2013 年版)的完成。
Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619838052. doi: 10.1177/1076029619838052.
4
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Otolaryngol Head Neck Surg. 2019 Jul;161(1):144-149. doi: 10.1177/0194599819835743. Epub 2019 Mar 12.
5
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J Obstet Gynaecol Res. 2019 Mar;45(3):657-664. doi: 10.1111/jog.13832. Epub 2018 Nov 4.
6
Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.《2018年心脏病和中风统计数据更新:美国心脏协会报告》
Circulation. 2018 Mar 20;137(12):e67-e492. doi: 10.1161/CIR.0000000000000558. Epub 2018 Jan 31.
7
The diagnosis and treatment of venous thromboembolism in asian patients.亚洲患者静脉血栓栓塞症的诊断与治疗
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8
Update on the management of venous thromboembolism.静脉血栓栓塞症的处理进展。
Cleve Clin J Med. 2017 Dec;84(12 Suppl 3):39-46. doi: 10.3949/ccjm.84.s3.04.
9
Widely Used Types and Clinical Applications of D-Dimer Assay.D-二聚体检测的广泛应用类型及临床应用
Lab Med. 2016 May;47(2):90-102. doi: 10.1093/labmed/lmw001. Epub 2016 Mar 25.
10
D-Dimer elevation and adverse outcomes.D - 二聚体升高与不良结局。
J Thromb Thrombolysis. 2015 Jan;39(1):55-9. doi: 10.1007/s11239-014-1101-6.

颅外耳科手术后患者的术后静脉血栓栓塞:病例系列

Post-operative venous thromboembolism in patients after extracranial otologic surgery: A case series.

作者信息

Mazmanyan Davit, Zhu Rongrong, Gao Juanjuan, Yang Yu, Zhong Jiake, Chen Junyan, Yi Haijin, Wu Weiwei

机构信息

Department of Vascular Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.

Department of Otolaryngology, Head & Neck Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.

出版信息

J Otol. 2024 Apr;19(2):59-62. doi: 10.1016/j.joto.2024.01.001. Epub 2024 Jan 2.

DOI:10.1016/j.joto.2024.01.001
PMID:39720111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11665942/
Abstract

OBJECTIVE

This study aimed to report 9 venous thromboembolism (VTE) cases after extracranial otologic surgery and analyze the potential risk factors.

STUDY DESIGN

Case series.

SETTING

Single tertiary-level academic center.

METHODS

Totally, 9 cases of VTE were identified among adults who underwent extracranial otologic surgery at our hospital from January 2018 to December 2020. Caprini risk scores were calculated, and comprehensive preoperative, operative, and postoperative clinical data within 14 days were collected to assess the evidence of VTE.

RESULTS

The median age of 9 patients was 64 years old. Among them, 7 (77.8%) patients presented with intramuscular vein thrombosis, 1 (11.1%) patient had deep vein thrombosis, and 1 (11.1%) patient experienced pulmonary embolism. Preoperatively, 8 (88.9%) patients had low or middle Caprini risk scores (≤4) with an average of 2.67 ± 0.47 points. The average Caprini scores for all patients were 4.44 ± 0.35 on postoperative day (POD)1 and 5.67 ± 0.64 on POD14. D-dimer levels were collected, indicating an average of 0.55 ± 0.17 mg/FEU preoperatively, 8.53 ± 3.94 mg/FEU at day 1, and 3.76 ± 0.45 mg/FEU at POD14. In postoperative period, 7 (77.8%) patients experienced vertigo/dizziness and/or head immobility/bed rest.

CONCLUSION

The present study highlighted that patients with low- and middle-risk of VTE undergoing otologic surgery should be also vigilant about postoperative VTE. Vertigo/dizziness and/or head immobility/bed rest in postoperative period should be considered as minor risk factors for developing VTE in patients undergoing extracranial otologic surgery. Conducting perioperative assessments, including Caprini risk score evaluation, D-dimer testing, and venous ultrasound of lower extremities, is recommended to ensure patients' safety.

摘要

目的

本研究旨在报告9例颅外耳科手术后发生静脉血栓栓塞症(VTE)的病例,并分析潜在的危险因素。

研究设计

病例系列研究。

研究地点

单一的三级学术中心。

方法

2018年1月至2020年12月期间,在我院接受颅外耳科手术的成年人中,共确诊9例VTE病例。计算Caprini风险评分,并收集术前、术中及术后14天内的综合临床资料,以评估VTE的证据。

结果

9例患者的中位年龄为64岁。其中,7例(77.8%)患者出现肌内静脉血栓形成,1例(11.1%)患者发生深静脉血栓形成,1例(11.1%)患者发生肺栓塞。术前,8例(88.9%)患者的Caprini风险评分为低或中(≤4分),平均分为2.67±0.47分。所有患者术后第1天(POD1)的平均Caprini评分为4.44±0.35分,术后第14天(POD14)为5.67±0.64分。收集了D-二聚体水平,术前平均为(0.55\pm0.17)mg/FEU,术后第1天为(8.53\pm3.94)mg/FEU,术后第14天为(3,76\pm0.45)mg/FEU。术后,7例(77.8%)患者出现眩晕/头晕和/或头部活动受限/卧床休息。

结论

本研究强调,接受耳科手术的VTE低风险和中风险患者术后也应警惕VTE。术后眩晕/头晕和/或头部活动受限/卧床休息应被视为颅外耳科手术患者发生VTE的次要危险因素。建议进行围手术期评估,包括Caprini风险评分评估、D-二聚体检测和下肢静脉超声检查,以确保患者安全。