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冠状动脉搭桥手术患者中欧洲心脏手术风险评估系统与终末期肝病模型之间的相关性。

The correlation between the European System for Cardiac Operative Risk Evaluation and the Model for End-Stage Liver Disease in patients with coronary artery bypass graft surgery.

作者信息

Ludusanu Andreea, Ciuntu Bogdan-Mihnea, Tanevski Adelina, Bernic Valentin, Tinica Grigore

机构信息

Department of Morpho-Functional Sciences I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania.

Department of General Surgery, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania.

出版信息

J Med Life. 2024 Oct;17(10):926-933. doi: 10.25122/jml-2024-0311.

Abstract

The Model for End-Stage Liver Disease (MELD) score is a widely used tool for quantifying hepatic dysfunction, providing greater accuracy and a wider range of values compared to the Child-Turcotte-Pugh (CTP) score, being also used in prioritizing patients who are eligible for liver transplantation. This study assessed the correlation between the MELD score and the European System for Cardiac Operative Risk Evaluation II (EuroSCORE II), a reliable system for categorizing risk levels in patients undergoing cardiovascular surgery. This retrospective study analyzed data from 589 patients who underwent coronary artery bypass grafting (CABG) at the Institute of Cardiovascular Diseases 'Prof. Dr. George I.M. Georgescu' in Iași between January 2011 and December 2020. Data collected included demographical, clinical, biochemical, and intraoperative parameters. The average MELD score was 6.09 ± 4.1 (median = 5.72), and the average EuroSCORE II was 6.28 ± 8 (median = 3.85). A significant but relatively modest positive relationship was found between the MELD score and EuroSCORE II, with a correlation coefficient of 0.23 and a corresponding significance level of 0.001. This study demonstrates a positive correlation between MELD and EuroSCORE II in patients who underwent CABG. Incorporating the MELD score into the preoperative risk assessment of cardiac surgery patients could help identify high-risk individuals and guide clinical decision-making.

摘要

终末期肝病模型(MELD)评分是一种广泛用于量化肝功能障碍的工具,与Child-Turcotte-Pugh(CTP)评分相比,它具有更高的准确性和更广泛的值范围,也用于对符合肝移植条件的患者进行优先级排序。本研究评估了MELD评分与欧洲心脏手术风险评估系统II(EuroSCORE II)之间的相关性,EuroSCORE II是一种用于对心血管手术患者的风险水平进行分类的可靠系统。这项回顾性研究分析了2011年1月至2020年12月期间在雅西的“Prof. Dr. George I.M. Georgescu”心血管疾病研究所接受冠状动脉旁路移植术(CABG)的589例患者的数据。收集的数据包括人口统计学、临床、生化和术中参数。平均MELD评分为6.09±4.1(中位数=5.72),平均EuroSCORE II为6.28±8(中位数=3.85)。在MELD评分与EuroSCORE II之间发现了显著但相对适度的正相关关系,相关系数为0.23,相应的显著性水平为0.001。本研究表明,在接受CABG的患者中,MELD与EuroSCORE II之间存在正相关。将MELD评分纳入心脏手术患者的术前风险评估中,有助于识别高危个体并指导临床决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acbb/11665745/a86a5eecc627/JMedLife-17-926-g001.jpg

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