Khan Zeeshan, Khan Zainab Aqeel, Ibrahim Muhammad
Department of Orthopaedics, Rehman Medical Institute, 5/B-2, Phase 5 Hayatabad, Peshawar, Pakistan.
Research and Development Department, AO Hospital, Nazimabad No. 4, Karachi, Pakistan.
J Clin Orthop Trauma. 2024 Dec 2;60:102854. doi: 10.1016/j.jcot.2024.102854. eCollection 2025 Jan.
The shoulder girdle and proximal humerus are common sites for neoplastic lesions be it benign or malignant. We aimed to evaluate the outcomes of a frugal method of reconstruction of the proximal humerus for neoplastic lesions at short to medium term follow-up.
Data for this retrospective case series was collected from an electronic data base held at the primary authors institution. All patients who had resection of the proximal humerus for any neoplastic lesion and reconstructed with a nail cement spacer were included in the study from January 2016 to January 2023. The functional outcomes were measured by Musculoskeletal tumour society score (MSTS) and the Toronto extremity salvage score (TESS). The survivorship and post-operative complications were also reported.
Twenty-two patients were available at final follow up with a mean follow-up time of 37 ± 18 months (range 12-81 months) with Ewing's sarcoma, giant cell tumour, osteosarcoma and metastatic disease as the commonest indications for surgery with a mean age of 29 ± 17 years. The Kaplan-Meier estimates indicated that the survival rate for 22 patients with endpoint (event) taken as death was 63.6 % and for endpoint taken (event) as implant failure was 95.5 % with mean survival time of 58.1 and 77 months respectively. At final follow up, the mean MSTS score was 23.6 ± 2.9 (78.7 %). One patient had superficial infection which settled with a short course of oral antibiotics and one patient had breakage of nail, which was revised.
These results prove that this frugal method of reconstruction is comparable with endoprosthesis when considering clinical and functional outcomes but significantly cost effective and should be considered for the individual patient.
无论是良性还是恶性肿瘤性病变,肩胛带和肱骨近端都是常见部位。我们旨在评估一种经济的肱骨近端肿瘤性病变重建方法在短期至中期随访中的效果。
本回顾性病例系列的数据来自第一作者所在机构的电子数据库。2016年1月至2023年1月期间,所有因任何肿瘤性病变切除肱骨近端并采用髓内钉骨水泥间隔器进行重建的患者均纳入本研究。功能结局通过肌肉骨骼肿瘤学会评分(MSTS)和多伦多肢体挽救评分(TESS)进行评估。还报告了生存率和术后并发症。
最终随访时共有22例患者,平均随访时间为37±18个月(范围12 - 81个月),最常见的手术指征为尤因肉瘤、骨巨细胞瘤、骨肉瘤和转移性疾病,平均年龄为29±17岁。Kaplan - Meier估计显示,以死亡为终点事件的22例患者生存率为63.6%,以植入物失败为终点事件的生存率为95.5%,平均生存时间分别为58.1个月和77个月。在最终随访时,平均MSTS评分为23.6±2.9(78.7%)。1例患者发生浅表感染,经短期口服抗生素治疗后痊愈,1例患者髓内钉断裂,进行了翻修。
这些结果证明,在考虑临床和功能结局时,这种经济的重建方法与人工关节假体相当,但成本效益显著,应针对个体患者予以考虑。