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1
Principles of Management of Extremity Skeletal Metastasis.四肢骨骼转移瘤的管理原则
Indian J Palliat Care. 2019 Oct-Dec;25(4):580-586. doi: 10.4103/IJPC.IJPC_90_19.
2
Is it safe to preserve the deltoid when resecting the proximal humerus for a primary malignant bone tumour? A comparative study.在为原发性恶性骨肿瘤切除近端肱骨时保留三角肌是否安全?一项对比研究。
Bone Joint J. 2017 Sep;99-B(9):1244-1249. doi: 10.1302/0301-620X.99B9.2016-1317.R1.
3
Is the Clavicula Pro Humero Technique of Value for Reconstruction After Resection of the Proximal Humerus in Children?儿童肱骨近端切除术后锁骨至肱骨技术重建是否具有价值?
Clin Orthop Relat Res. 2017 Oct;475(10):2550-2561. doi: 10.1007/s11999-017-5438-y. Epub 2017 Jul 11.
4
Endoprosthetic replacement versus cement spacer in reconstruction of proximal humerus after tumor resection: Cost and benefits.肿瘤切除术后近端肱骨重建中人工关节置换与骨水泥间隔器的比较:成本与效益
J Orthop Surg (Hong Kong). 2017 May-Aug;25(2):2309499017713937. doi: 10.1177/2309499017713937.
5
What is the Optimal Reconstruction Option after the Resection of Proximal Humeral Tumors? A Systematic Review.肱骨近端肿瘤切除术后的最佳重建方案是什么?一项系统评价。
Open Orthop J. 2017 Mar 22;11:203-211. doi: 10.2174/1874325001711010203. eCollection 2017.
6
Novel modification of second generation intramedullary PMMA cementing technique for narrow upper and lower extremity canals.用于狭窄的上肢和下肢髓腔的第二代髓内聚甲基丙烯酸甲酯骨水泥固定技术的新型改良
J Clin Orthop Trauma. 2016 Jan-Mar;7(1):66-9. doi: 10.1016/j.jcot.2015.08.006. Epub 2015 Sep 16.
7
Proximal humerus allograft prosthetic composites: technique, outcomes, and pearls and pitfalls.肱骨近端同种异体移植假体复合物:技术、结果及要点与陷阱
Curr Rev Musculoskelet Med. 2015 Dec;8(4):324-33. doi: 10.1007/s12178-015-9306-7.
8
Synthetic mesh improves shoulder function after intraarticular resection and prosthetic replacement of proximal humerus.合成补片可改善肱骨头近端关节内切除及假体置换术后的肩部功能。
Clin Orthop Relat Res. 2015 Apr;473(4):1464-71. doi: 10.1007/s11999-015-4139-7. Epub 2015 Jan 21.
9
Treatment and outcome of malignant bone tumors of the proximal humerus: biological versus endoprosthetic reconstruction.肱骨近端恶性骨肿瘤的治疗与预后:生物重建与人工关节置换重建的对比
BMC Musculoskelet Disord. 2014 Mar 7;15:69. doi: 10.1186/1471-2474-15-69.
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Outcome after reconstruction of the proximal humerus for tumor resection: a systematic review.肱骨近端骨肿瘤切除后重建的结果:系统评价。
Clin Orthop Relat Res. 2014 Jul;472(7):2245-53. doi: 10.1007/s11999-014-3474-4. Epub 2014 Jan 28.

植入式骨水泥间隔物——肿瘤切除后肱骨近端缺损重建的经济有效解决方案。

Implant cement spacer-a cost-effective solution for reconstruction of proximal humerus defects after tumor resection.

作者信息

Gulia Ashish, Raj B K Amrath, Gupta Srinath, Patil Akshay, Puri Ajay

机构信息

Bone and Soft Tissue Services, Dept of Surgical Oncology, Tata Memorial Hospital, And Homi Bhabha National Institute (HBNI), Mumbai, India.

Clinical Research Secretariat, Tata Memorial Hospital, Parel, Mumbai, India.

出版信息

J Clin Orthop Trauma. 2021 Sep 13;22:101574. doi: 10.1016/j.jcot.2021.101574. eCollection 2021 Nov.

DOI:10.1016/j.jcot.2021.101574
PMID:34722144
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8531854/
Abstract

The proximal humerus is a common location for both primary benign and malignant bone tumors and may require sacrificing deltoid muscles, axillary nerve and/or rotator cuff along with proximal humerus resection. Thus, post operatively shoulder movements are restricted. The main goals of reconstruction are to maintain a stable shoulder so that the function of elbow and hand can be optimized. Various reconstruction options are available after proximal humerus resection. We present our experience in using implant-cement spacers as a primary reconstruction option for limb salvage in the primary tumors of proximal humerus. All cases were retrieved from our prospectively maintained surgical database. 142 patients (96 males and 46 females) with a median age of 17.5 years (3-70 years) were operated with implant cement spacer between January 2006 and April 2019. Median follow up was 34 months (1-174 months). Functional outcome of the surgery was assessed in survivors by Musculoskeletal Tumor Society score (MSTS). Implant survival was assessed by Kaplan Meier analysis and competing risk analysis. On last follow up, out of 142 cases, 81 patients had died, 54 are alive and seven were lost to follow up. 18(13%) patients underwent revision surgery for symptomatic proximal migration, implant failure or infection. Four (2.8%) patients underwent forequarter amputation for local recurrence. The five years implant survival (IS) by Kaplan Meier analysis was 79.6% and as per competing risk analysis, the chances of implant revision are 12% and 18% at five and ten years respectively. Mean MSTS score in survivors was 71% (60-80%). Implant cement spacer is a cost-effective alternative for reconstruction of proximal humerus with revision rates and function comparable to other reconstructions in cases where deltoid, axillary nerve and/or rotator cuff are excised.

摘要

肱骨近端是原发性良性和恶性骨肿瘤的常见部位,在进行肱骨近端切除时可能需要连同三角肌、腋神经和/或肩袖一并切除。因此,术后肩部活动受到限制。重建的主要目标是保持肩部稳定,以便优化肘部和手部的功能。肱骨近端切除术后有多种重建选择。我们介绍了使用植入物-骨水泥间隔物作为肱骨近端原发性肿瘤保肢的主要重建选择的经验。所有病例均来自我们前瞻性维护的手术数据库。2006年1月至2019年4月期间,对142例患者(96例男性和46例女性)进行了植入物骨水泥间隔物手术,中位年龄为17.5岁(3至70岁)。中位随访时间为34个月(1至174个月)。通过肌肉骨骼肿瘤学会评分(MSTS)对幸存者的手术功能结果进行评估。通过Kaplan Meier分析和竞争风险分析评估植入物存活率。在最后一次随访时,142例病例中,81例患者死亡,54例存活,7例失访。18例(13%)患者因症状性近端移位、植入物失败或感染接受了翻修手术。4例(2.8%)患者因局部复发接受了前半侧截肢。通过Kaplan Meier分析,五年植入物存活率(IS)为79.6%,根据竞争风险分析,在五年和十年时植入物翻修的几率分别为12%和18%。幸存者的平均MSTS评分为71%(60-80%)。在切除三角肌、腋神经和/或肩袖的病例中,植入物骨水泥间隔物是一种具有成本效益的肱骨近端重建替代方案,其翻修率和功能与其他重建方法相当。