Suppr超能文献

植入式骨水泥间隔物——肿瘤切除后肱骨近端缺损重建的经济有效解决方案。

Implant cement spacer-a cost-effective solution for reconstruction of proximal humerus defects after tumor resection.

作者信息

Gulia Ashish, Raj B K Amrath, Gupta Srinath, Patil Akshay, Puri Ajay

机构信息

Bone and Soft Tissue Services, Dept of Surgical Oncology, Tata Memorial Hospital, And Homi Bhabha National Institute (HBNI), Mumbai, India.

Clinical Research Secretariat, Tata Memorial Hospital, Parel, Mumbai, India.

出版信息

J Clin Orthop Trauma. 2021 Sep 13;22:101574. doi: 10.1016/j.jcot.2021.101574. eCollection 2021 Nov.

Abstract

The proximal humerus is a common location for both primary benign and malignant bone tumors and may require sacrificing deltoid muscles, axillary nerve and/or rotator cuff along with proximal humerus resection. Thus, post operatively shoulder movements are restricted. The main goals of reconstruction are to maintain a stable shoulder so that the function of elbow and hand can be optimized. Various reconstruction options are available after proximal humerus resection. We present our experience in using implant-cement spacers as a primary reconstruction option for limb salvage in the primary tumors of proximal humerus. All cases were retrieved from our prospectively maintained surgical database. 142 patients (96 males and 46 females) with a median age of 17.5 years (3-70 years) were operated with implant cement spacer between January 2006 and April 2019. Median follow up was 34 months (1-174 months). Functional outcome of the surgery was assessed in survivors by Musculoskeletal Tumor Society score (MSTS). Implant survival was assessed by Kaplan Meier analysis and competing risk analysis. On last follow up, out of 142 cases, 81 patients had died, 54 are alive and seven were lost to follow up. 18(13%) patients underwent revision surgery for symptomatic proximal migration, implant failure or infection. Four (2.8%) patients underwent forequarter amputation for local recurrence. The five years implant survival (IS) by Kaplan Meier analysis was 79.6% and as per competing risk analysis, the chances of implant revision are 12% and 18% at five and ten years respectively. Mean MSTS score in survivors was 71% (60-80%). Implant cement spacer is a cost-effective alternative for reconstruction of proximal humerus with revision rates and function comparable to other reconstructions in cases where deltoid, axillary nerve and/or rotator cuff are excised.

摘要

肱骨近端是原发性良性和恶性骨肿瘤的常见部位,在进行肱骨近端切除时可能需要连同三角肌、腋神经和/或肩袖一并切除。因此,术后肩部活动受到限制。重建的主要目标是保持肩部稳定,以便优化肘部和手部的功能。肱骨近端切除术后有多种重建选择。我们介绍了使用植入物-骨水泥间隔物作为肱骨近端原发性肿瘤保肢的主要重建选择的经验。所有病例均来自我们前瞻性维护的手术数据库。2006年1月至2019年4月期间,对142例患者(96例男性和46例女性)进行了植入物骨水泥间隔物手术,中位年龄为17.5岁(3至70岁)。中位随访时间为34个月(1至174个月)。通过肌肉骨骼肿瘤学会评分(MSTS)对幸存者的手术功能结果进行评估。通过Kaplan Meier分析和竞争风险分析评估植入物存活率。在最后一次随访时,142例病例中,81例患者死亡,54例存活,7例失访。18例(13%)患者因症状性近端移位、植入物失败或感染接受了翻修手术。4例(2.8%)患者因局部复发接受了前半侧截肢。通过Kaplan Meier分析,五年植入物存活率(IS)为79.6%,根据竞争风险分析,在五年和十年时植入物翻修的几率分别为12%和18%。幸存者的平均MSTS评分为71%(60-80%)。在切除三角肌、腋神经和/或肩袖的病例中,植入物骨水泥间隔物是一种具有成本效益的肱骨近端重建替代方案,其翻修率和功能与其他重建方法相当。

相似文献

本文引用的文献

1
Principles of Management of Extremity Skeletal Metastasis.四肢骨骼转移瘤的管理原则
Indian J Palliat Care. 2019 Oct-Dec;25(4):580-586. doi: 10.4103/IJPC.IJPC_90_19.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验