Alberto Flores Paños, Luis Marin Martinez, Alberto Espinosa Sanchez, Kyriakos Georgios, Rios Vergara Antonio-Javier, Enrique Hernandez Alonso
Endocrinology and Nutrition Department, Hospital General Universitario Santa Lucía, Murcia, Spain.
Pathology Department, Hospital General Universitario Santa Lucía, Murcia, Spain.
Pan Afr Med J. 2024 Oct 3;49:26. doi: 10.11604/pamj.2024.49.26.43171. eCollection 2024.
The thyroid is a rare site for finding tumor metastases. Renal, colorectal, pulmonary, and mammary origin are the most frequent primary neoplasms. Clinical suspicion, early diagnosis, and active surveillance are important during follow-up. Thyroid ultrasound and fine needle aspiration thyroid ultrasound are crucial during follow-up. We present a case of a 66-year-old male who was referred to our Endocrinology and Nutrition Department of the Hospital General Universitario Santa Lucía due to a multinodular goiter. The patient had no symptoms of hyperthyroidism or hypothyroidism. No weight loss or constitutional syndrome was reported. The patient was suffering from a renal clear cell carcinoma with T3aNxM0 stage operated on using a nephrectomy technique in 2012. In a new follow-up, a positron emission tomography-computed tomography (PET-CT) scan was conducted and a multinodular goiter was found with an increase in size and metabolism at the expense of a right thyroid nodule and thyroid ultrasound and fine needle aspiration thyroid ultrasound was requested with the diagnosis of renal cell carcinoma metastasis. We present a rare case report since both metastases (thyroid and pulmonary) could be surgically intervened with curative intent and a review of the literature. This case emphasizes the importance of considering a metastatic origin when finding a thyroid nodule in a patient with a previous history of clear renal cell carcinoma even years after treatment with curative intent.
甲状腺是肿瘤转移的罕见部位。肾、结肠直肠、肺和乳腺来源是最常见的原发性肿瘤。随访期间临床怀疑、早期诊断和积极监测很重要。甲状腺超声和甲状腺细针穿刺超声在随访中至关重要。我们报告一例66岁男性患者，因多结节性甲状腺肿转诊至圣卢西亚大学综合医院内分泌与营养科。患者无甲亢或甲减症状。未报告体重减轻或全身综合征。该患者患有肾透明细胞癌，2012年采用肾切除术进行手术，分期为T3aNxM0。在新的随访中，进行了正电子发射断层扫描-计算机断层扫描（PET-CT），发现多结节性甲状腺肿，大小和代谢增加，以右侧甲状腺结节为代价，并要求进行甲状腺超声和甲状腺细针穿刺超声检查，诊断为肾细胞癌转移。我们呈现一份罕见病例报告，因为两种转移（甲状腺和肺）都可以进行有治愈意图的手术干预，并对文献进行综述。该病例强调，即使在进行了有治愈意图的治疗多年后，对于有肾透明细胞癌既往史的患者，发现甲状腺结节时考虑转移起源的重要性。
