Guo Longrun, He Zhufa
Department of Rehabilitation Medicine, The Third People's Hospital of Ganzhou City, Ganzhou, Jiangxi, China.
Department of Psychiatry, The Third People's Hospital of Ganzhou City, Ganzhou, Jiangxi, China.
Front Psychiatry. 2024 Dec 10;15:1478359. doi: 10.3389/fpsyt.2024.1478359. eCollection 2024.
Depression is the most common mental illness among older adults, with substantial and persistent mood depression as the main clinical feature, which is unfavorable for improvement. The clinical manifestations can range from melancholy to grief or even numbness. Approximately one-third of older adult patients exhibit physical discomfort as the first symptom; dysgeusia as the first symptom, is very rare in clinical practice. Dysgeusia is a clinical symptom with no specific objective indicator; thus, the likelihood of misdiagnosis and missed diagnosis is high.
In this study, a 60-year-old female housewife with elementary school as her highest level of education, presented to the outpatient department with dysgeusia, poor sleep, and poor mood persisting for >1 year, which aggravated 2 weeks before hospital visit. Psychiatric examination showed clear consciousness; the patient was cleanly and timely dressed and demonstrated self-care but had a worrisome expression. Using the diagnostic criteria of the International Classification of Diseases (10 edition), a diagnosis of a major depressive episode with psychotic symptoms was made. Following pharmacological and psychological treatment, the patient's condition improved. The patient was compliant to treatment (10 mg/day of escitalopram), had a stable mood, good sleep, and no dysgeusia at >2 years of follow-up as an outpatient. She was able to do housework and take care of her children normally and did not complain about any other issues.
Physical discomfort is a very common complaint in older patients with depression. If persistent physical symptoms do not improve after repeated medical treatment, timely assessment of the patient's mental state or psychiatric referral should be considered to diagnose geriatric depression. Timely pharmacological and psychological therapy are the preferred treatment for older adults.
抑郁症是老年人中最常见的精神疾病,以显著而持久的心境低落为主要临床特征,不利于病情改善。临床表现可从忧郁到悲伤甚至麻木。约三分之一的老年患者以身体不适为首发症状;以味觉障碍为首发症状在临床实践中非常罕见。味觉障碍是一种无特定客观指标的临床症状;因此,误诊和漏诊的可能性很高。
在本研究中,一名60岁的家庭主妇,最高学历为小学,因味觉障碍、睡眠差和情绪低落持续超过1年就诊于门诊,入院前2周病情加重。精神检查显示意识清楚;患者穿着整洁及时,具备自理能力,但表情忧虑。根据国际疾病分类(第10版)的诊断标准,诊断为伴有精神病性症状的重度抑郁发作。经过药物和心理治疗,患者病情好转。患者依从治疗(艾司西酞普兰10毫克/天),在门诊随访2年多来情绪稳定、睡眠良好且无味觉障碍。她能够正常做家务和照顾孩子,未抱怨任何其他问题。
身体不适是老年抑郁症患者非常常见的主诉。如果反复就医后持续性躯体症状仍未改善,应考虑及时评估患者的精神状态或转诊精神科以诊断老年抑郁症。及时的药物和心理治疗是老年人的首选治疗方法。