Whitington P M
Dev Biol. 1985 Feb;107(2):537-40. doi: 10.1016/0012-1606(85)90335-5.
Metathoracic limb buds were removed unilaterally from Locusta migratoria embryos at 30% of embryonic development, thereby depriving limb-innervating neurons of the opportunity of innervating their normal target muscles. The operated embryos were allowed to hatch and develop to adulthood, and then the connections between the identified limb motorneuron Fast Extensor Tibiae (FETi) and body wall muscles on the operated side of the segment were determined electrophysiologically. FETi innervated a number of foreign muscles in the ipsilateral body wall in limb-ablated locusts, showing that this neuron is not programmed to exclusively innervate its normal target muscle.
在胚胎发育至30%时，单侧切除飞蝗胚胎的后胸肢体芽，从而使支配肢体的神经元失去支配其正常靶肌肉的机会。让手术处理后的胚胎孵化并发育至成年，然后通过电生理学方法确定已鉴定的肢体运动神经元快速胫节伸肌（FETi）与该节段手术侧体壁肌肉之间的连接。在肢体切除的飞蝗中，FETi支配同侧体壁的许多异常肌肉，这表明该神经元并非被设定为仅支配其正常靶肌肉。
