顶眼蝾螈视前区前部出现永久性损伤后三碘甲状腺原氨酸生成增加。

Enhanced triiodothyronine production in crested newts bearing permanent lesions to the anterior preoptic area.

作者信息

Mazzi V, Peyrot A, Vellano C, Colucci D

出版信息

Gen Comp Endocrinol. 1985 Jan;57(1):43-6. doi: 10.1016/0016-6480(85)90198-4.

Abstract

In the crested newt, permanent lesions to the anterior preoptic area brought about an enhancement of triiodothyronine (T3) production. This was not mediated by prolactin, since the effect was demonstrable also in ergocryptine (CB 154)-treated animals. The observed rise in circulating T3 levels in the ergocryptine-treated surgical animals confirms that lesions to the anterior preoptic area stimulate pituitary thyrotrophic activity, resulting in the activation of the thyroid gland.

摘要

在有冠蝾螈中，视前区前部的永久性损伤导致三碘甲状腺原氨酸（T3）分泌增加。这并非由催乳素介导，因为在麦角隐亭（CB 154）处理的动物中也可观察到该效应。在接受麦角隐亭处理的手术动物中观察到的循环T3水平升高证实，视前区前部的损伤刺激了垂体促甲状腺素活性，从而导致甲状腺的激活。