Bratberg Aase, Nygaard Ilah, Løhne Kari, Gustavsen Ingebjørg, Opdal Mimi Stokke
Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Basic Clin Pharmacol Toxicol. 2025 Jan;136(1):e14118. doi: 10.1111/bcpt.14118.
We examined the number of patients tested for serum ethanol concentration (SEC) at admission to a large Emergency Department (ED) and the relationship of SEC with sex and age. SEC was analysed by enzymatic method. We retrieved SEC in patient samples from the ED during 2015-2020 from the laboratory information system. Altogether, 174 378 patients were admitted, and 7.3% were tested for SEC. Of these, 35.3% had a positive test. The percentage of patients tested increased from 4.8% in 2015 to 14.4% in 2020. A total of 416 patients had more than one positive SEC. For individual data, we included the first positive test per patient, n = 3607. Of these, 73% were men and 27% were women. The median SEC for both men and women was 1.9 g/L. About 4.4% had a SEC ≥ 3.5 g/L. The median SEC in patients aged 30-59 years was 0.2 g/L higher than the 12-29 and ≥ 60 age groups. In conclusion, the increase in the percentage of patients tested did not lead to a corresponding increase in ethanol-positive tests. There was a large predominance of men, the median SEC was the same for men and women and highest in the 30-59 age group.
我们调查了一家大型急诊科（ED）收治患者时检测血清乙醇浓度（SEC）的患者数量，以及SEC与性别和年龄的关系。采用酶法分析SEC。我们从实验室信息系统中检索了2015年至2020年期间ED患者样本中的SEC。共有174378名患者入院，其中7.3%接受了SEC检测。其中，35.3%检测结果呈阳性。接受检测的患者百分比从2015年的4.8%增至2020年的14.4%。共有416名患者的SEC检测不止一次呈阳性。对于个体数据，我们纳入了每位患者的首次阳性检测结果，n = 3607。其中，73%为男性，27%为女性。男性和女性的SEC中位数均为1.9g/L。约4.4%的患者SEC≥3.5g/L。年龄在30 - 59岁的患者SEC中位数比12 - 29岁及≥60岁年龄组高0.2g/L。总之，接受检测患者百分比的增加并未导致乙醇阳性检测结果相应增加。男性占比很大，男性和女性的SEC中位数相同，且在30 - 59岁年龄组最高。
