BACKGROUND: In the context of China, where the demographic trend of population aging intertwines with the rapid advancement of information digitalization, rural older adult individuals, who are part of a vulnerable population, are witnessing a deteriorating depression status. The proliferation of rural e-commerce, which fuels the digital economic revolution in rural areas, is concurrently affecting the depressive symptoms among rural older adult individuals. METHODS: This study uses longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS) and applies a multi-period Difference-in-Differences (DID) model to explore how rural e-commerce affects the depressive symptoms among rural older adult individuals. RESULTS: The findings indicate that the development of rural e-commerce can indeed improve the depressive symptoms among rural older adult individuals, with a particularly pronounced effect on those residing in the eastern and central regions of China, as well as those who do not live with their children. The mechanism analysis indicates that e-commerce improves depressive symptoms among rural older adult individuals by enhancing social interaction frequency and increasing financial support by children. CONCLUSION: Based on these insights, we recommend a targeted approach to implementing e-commerce policies in rural areas, focusing on innovative methods to improve the depressive symptoms among rural older adult individuals.