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肠道卡波西肉瘤——表现为貌似溃疡性结肠炎

Kaposi's sarcoma of the bowel--presenting as apparent ulcerative colitis.

作者信息

Weber J N, Carmichael D J, Boylston A, Munro A, Whitear W P, Pinching A J

出版信息

Gut. 1985 Mar;26(3):295-300. doi: 10.1136/gut.26.3.295.

Abstract

Persistent diarrhoea with mucus-production developed in a 37 year homosexual man, and an initial diagnosis of ulcerative colitis was made after barium enema examination and rectal biopsy. The patient later developed cutaneous lesions which proved to be Kaposi's sarcoma, and the bowel lesion was also subsequently shown to be Kaposi's sarcoma. This tumour occurred as a manifestation of the acquired immune deficiency syndrome (AIDS). The patient was treated with alpha interferon, with partial regression of the skin lesions, but progression of the bowel tumour. Because of severe bowel symptoms, including episodes of subacute intestinal obstruction, the localised bowel disease was treated with radiotherapy. In view of the increasing incidence of AIDS, a diagnosis of Kaposi's sarcoma must be considered in homosexual men presenting with persistent diarrhoea, for which no infectious cause can be demonstrated.

摘要

一名37岁的同性恋男子出现了伴有黏液分泌的持续性腹泻,在进行钡剂灌肠检查和直肠活检后,初步诊断为溃疡性结肠炎。该患者后来出现了皮肤病变,经证实为卡波西肉瘤,肠道病变随后也被证明是卡波西肉瘤。这种肿瘤是获得性免疫缺陷综合征(艾滋病)的一种表现。患者接受了α干扰素治疗,皮肤病变部分消退,但肠道肿瘤进展。由于严重的肠道症状,包括亚急性肠梗阻发作,对局限性肠道疾病进行了放射治疗。鉴于艾滋病发病率不断上升,对于出现持续性腹泻且无法证明有感染原因的同性恋男性,必须考虑卡波西肉瘤的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d5/1432641/2dad58608238/gut00376-0092-a.jpg

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