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人乳头瘤病毒疫苗接种对青春期女性宫颈癌的影响:一项叙述性综述。

The Impact of HPV Vaccination on Cervical Cancer in adolescent females: A narrative review.

作者信息

Bhalerao Vijay, Gotarkar Shashank, Muneshwar Komal

机构信息

Department of Community Medicine, Jawaharlal Nehru Medical College, School of Epidemiology and Public Health, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.

Department of Community Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.

出版信息

J Family Med Prim Care. 2024 Nov;13(11):4775-4782. doi: 10.4103/jfmpc.jfmpc_235_24. Epub 2024 Nov 18.

Abstract

To effectively prevent cervical cancer, a leading cause of global morbidity and mortality among women, widespread adoption of the HPV vaccine has a well-established link to human papillomavirus (HPV) infection. HPV vaccine must be the vaccine's effectiveness in reducing HPV infections, and subsequent cervical lesions have been extensively demonstrated, marking a pivotal milestone in public health. Important research highlights the vaccine's safety profile, allaying worries and promoting trust in its application. By targeting HPV strains responsible for a majority of cervical cancer cases, vaccination emerges as a strategic intervention to curb the burden of this malignancy. The strategy is used to search PubMed and Google Scholar, with only free full-text and English language study included. However, addressing existing misconceptions and ensuring equitable vaccine access remains imperative. Informed decision making is pivotal, necessitating comprehensive public health initiatives that educate communities about the vaccine's benefits. Encouragingly, successful vaccination programs in various regions have demonstrated tangible reductions in HPV prevalence and cervical cancer incidence. This review concludes by emphasizing the urgent need for global collaboration to integrate HPV vaccination into routine immunization schedules, thereby fortifying the collective effort to mitigate cervical cancer's impact. As a cost-effective, evidence-based strategy, widespread HPV vaccination stands as a linchpin in the ongoing battle against cervical cancer, promising a healthier future for women worldwide.

摘要

为有效预防宫颈癌(全球女性发病和死亡的主要原因之一),广泛接种人乳头瘤病毒(HPV)疫苗与HPV感染有着明确的关联。HPV疫苗在减少HPV感染以及后续宫颈病变方面的有效性已得到广泛证实,这标志着公共卫生领域的一个关键里程碑。重要研究突出了该疫苗的安全性,消除了人们的担忧并促进了对其应用的信任。通过针对导致大多数宫颈癌病例的HPV毒株,疫苗接种成为遏制这种恶性肿瘤负担的一项战略干预措施。本策略用于检索PubMed和谷歌学术,仅纳入免费全文和英文研究。然而,解决现有误解并确保公平的疫苗可及性仍然至关重要。明智的决策至关重要,需要开展全面的公共卫生倡议,向社区宣传疫苗的益处。令人鼓舞的是,不同地区成功的疫苗接种项目已证明HPV流行率和宫颈癌发病率切实下降。本综述最后强调,迫切需要全球合作将HPV疫苗接种纳入常规免疫计划,从而加强集体努力以减轻宫颈癌的影响。作为一种具有成本效益且基于证据的策略,广泛接种HPV疫苗是当前抗击宫颈癌斗争的关键,有望为全球女性带来更健康的未来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/725d/11668371/e95bb6fcda6d/JFMPC-13-4775-g001.jpg

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