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过量服用非处方止咳糖浆导致儿童出现严重症状——病例报告

Overzealous over-the-counter cough syrup ingestion leading to serious manifestation in a child - A case report.

作者信息

Yadav Dinkar, Verma Hunny, Yadav Neha, Bhalla Kapil

机构信息

Department of Pediatrics, PGIMS, Rohtak, Haryana, India.

Department of Ophthalmology, PGIMS Rohtak, Haryana, India.

出版信息

J Family Med Prim Care. 2024 Nov;13(11):5367-5369. doi: 10.4103/jfmpc.jfmpc_130_24. Epub 2024 Nov 18.

DOI:10.4103/jfmpc.jfmpc_130_24
PMID:39723020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11668449/
Abstract

Cough is a protective reflex that allows clearance of secretions from upper respiratory tract. It is not a disease by itself but a symptom of underlying disease. In a majority of cases, it is self-limiting and requires only supportive care. But over-the-counter cough syrups are inadvertently used to relieve cough in Indian settings. We hereby report a case of a 6-year-old girl child who presented to pediatrics emergency services with complaints of loss of consciousness and abnormal body movement after ingestion of dextromethorphan and chlorpheniramine containing cough syrup. All investigations including cerebrospinal fluid examination, neuroimaging, and electroencephalogram revealed no significant abnormality. The child was admitted for 5 days and discharged after that in stable conditions.

摘要

咳嗽是一种保护性反射,可使上呼吸道分泌物得以清除。它本身并非一种疾病,而是潜在疾病的症状。在大多数情况下,咳嗽是自限性的,仅需支持性护理。但在印度,非处方止咳糖浆却被人们随意用于缓解咳嗽。我们在此报告一例6岁女童的病例,该女童因摄入含有右美沙芬和氯苯那敏的止咳糖浆后出现意识丧失和身体异常运动,被送往儿科急诊。包括脑脊液检查、神经影像学检查和脑电图检查在内的所有检查均未发现明显异常。该患儿住院5天后,病情稳定出院。

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本文引用的文献

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Life-threatening pediatric dextromethorphan polistirex overdose.危及生命的儿童右美沙芬聚维酮碘过量。
Am J Emerg Med. 2022 Nov;61:233.e1-233.e2. doi: 10.1016/j.ajem.2022.08.006. Epub 2022 Aug 8.
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Dextromethorphan-Induced Altered Level of Consciousness in Children: A Case Series.右美沙芬致儿童意识改变:病例系列研究。
Curr Drug Saf. 2023;18(3):389-392. doi: 10.2174/1574886317666220606145809.
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