Luedke Jessica C, Vargas Gray, Malone Laura A, Parker Kathleen H, Ng Rowena
University of South Carolina, Columbia, SC, USA.
Kennedy Krieger Institute, Baltimore, MD, USA.
Clin Neuropsychol. 2025 Jul;39(5):1286-1300. doi: 10.1080/13854046.2024.2445269. Epub 2024 Dec 26.
To determine the clinical utility of teleneuropsychology (teleNP) services in screening for cognitive concerns in a population of children and adolescents presenting with long COVID. This cross-sectional study evaluated 76 pediatric patients (64% female, = 13.48, = 2.97, range = 5 to 18 years) with long COVID referred for a neuropsychological evaluation due to persistent cognitive symptoms following their COVID infection. Of these 76 patients, 33 were tested in person, while 43 were tested via teleNP at home. Patients were administered a brief testing battery designed for use in-person or through teleNP services. Tests administered included the WASI-II (Intellectual Functioning), D-KEFS Verbal Fluency (Executive Functioning/Shifting), Oral Version of the Symbol Digit Modalities Test (Processing Speed), ChAMP List (Learning and Memory), WAIS-IV/WISC-V Digit Span (Working Memory), and TEA-Ch Score and Score DT (Sustained Auditory Attention and Divided Attention). Differences in scores between those evaluated in-person or teleNP were computed using analyses of variance and Bayesian statistics across measures. Differences in the proportion of those scoring in the below average range (< 9 percentile) were also computed. Findings revealed similar performance for patients tested in-person and patients tested by teleNP modality across measures. The present study provides preliminary evidence for the clinical utility of teleNP services in pediatric long COVID patients on a cognitive screening battery. These results lend support for expanding teleNP services to pediatric patients with long COVID to assess neurocognitive functioning, which is particularly important given scarcity of specialty long COVID clinics.
为了确定远程神经心理学(teleNP)服务在筛查患有新冠后综合征的儿童和青少年认知问题方面的临床效用。这项横断面研究评估了76名患有新冠后综合征的儿科患者(64%为女性,平均年龄 = 13.48岁,标准差 = 2.97,年龄范围 = 5至18岁),这些患者因新冠感染后持续存在认知症状而被转介进行神经心理学评估。在这76名患者中,33人接受了现场测试,而43人通过teleNP在家中接受测试。患者接受了一套专为现场使用或通过teleNP服务设计的简短测试。所进行的测试包括韦氏儿童智力量表第二版(智力功能)、Delis-Kaplan执行功能系统言语流畅性测验(执行功能/转换)、符号数字模式测验口语版(处理速度)、ChAMP列表(学习和记忆)、韦氏成人智力量表第四版/韦氏儿童智力量表第五版数字广度测验(工作记忆),以及TEA-Ch分数和得分DT(持续听觉注意力和分散注意力)。使用方差分析和贝叶斯统计方法计算现场评估或通过teleNP评估的患者在各测量指标上的得分差异。还计算了得分在低于平均范围(<第9百分位数)的患者比例差异。研究结果显示,现场测试的患者和通过teleNP模式测试的患者在各测量指标上表现相似。本研究为teleNP服务在患有新冠后综合征的儿科患者认知筛查测试中的临床效用提供了初步证据。这些结果支持将teleNP服务扩展到患有新冠后综合征的儿科患者,以评估神经认知功能,鉴于专门的新冠后综合征诊所稀缺,这一点尤为重要。